US pharmacy pricing
Tyrvaya Cost Without Insurance — US Pharmacy Price Guide
Lowest price found · US pharmacies
$685.72/fill
for Tyrvaya, across the pharmacies in our data
US pharmacy prices — 0.03mg/act
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $685.72Lowest | $688.72 | $97.59 |
 Harris Teeter Pharmacy | $685.72Lowest | $688.72 | $97.59 |
 Walgreens | $721.03 | $724.03 | $97.59 |
 Food Lion | $721.08 | $721.08 | $97.59 |
 Publix | $726.47 | $729.47 | $97.59 |
 CVS Pharmacy | $729.70 | $732.70 | $97.59 |
 Walmart Neighborhood Market | $736.57 | $739.57 | $97.59 |
 Walmart Pharmacy | $736.57 | $739.57 | $97.59 |
 Costco | $740.25 | $743.25 | $97.59 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Tyrvaya.
Frequently asked questions
How much does Tyrvaya (Tyrvaya) cost without insurance?
Our most recent US pharmacy data shows a low of roughly $685.72 for Tyrvaya with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
Does Tyrvaya have a generic equivalent?
Generic and brand-name pricing for Tyrvaya is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
What determines the cost of Tyrvaya with health insurance?
The out-of-pocket cost for Tyrvaya under an insurance plan depends entirely on the specific plan's formulary and benefit structure. While many commercial plans provide some coverage, patients are usually responsible for copayments or coinsurance. The amount can vary widely. It's important to check with your insurance provider or pharmacist to understand your exact cost. In some instances, savings from a pharmacy discount program may offer a lower price than your insurance copay.
Is a generic version of Tyrvaya available?
No, Tyrvaya is currently only available as a brand-name medication. There is no generic equivalent on the market. The drug is manufactured by Oyster Point Pharma, and its patent protection is expected to last until around 2035, after which a generic version may become available.
What is Tyrvaya used for?
Tyrvaya is a prescription nasal spray used to treat the symptoms of dry eye disease. It is typically considered when other treatments, such as artificial tears, have not provided adequate relief. The medication contains varenicline, which acts on receptors in the nervous system to stimulate the body's natural tear production, helping to reduce the discomfort associated with dry eyes.