Full price comparison · US & Canada
Akynzeo Prices — US Pharmacy Cost vs Canada
Price comparison
See both prices
We don't have a directly comparable per-unit price for Akynzeo yet — the full breakdown is below.
US · discount card
$697.16
per fill
Lowest listed pharmacy price
Canada
$121.26
per tablet
Lowest listed pharmacy price
US pharmacy prices — 1 capsules
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $697.16Lowest | $700.16 | $1,033.54 |
 Harris Teeter Pharmacy | $697.16Lowest | $700.16 | $1,033.54 |
 Food Lion | $733.02 | $733.02 | $1,033.54 |
 Walgreens | $733.03 | $736.03 | $1,033.54 |
 Publix | $738.55 | $741.55 | $1,033.54 |
 CVS Pharmacy | $741.55 | $744.55 | $1,033.54 |
 Costco | $752.60 | $755.60 | $1,033.54 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
Initial · 300 mg/500 mcgfrom $481.74
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 GoldStarMeds.com | $160.58 | — | $0.00 | $481.74Lowest |
 1800RxOnline.com | $178.42 | — | $0.00 | $535.27 |
Initial · 300 mg/.5 mgfrom $135.65
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 CanadianPharmacyAdvantage.com | $121.26 | — | Free | $363.79Lowest |
 CanadaPharmacies.com | $125.00 | — | Free | $374.99 |
| CanadianPharmacyAdvantage.com | $135.65 | — | Free | $135.65 |
| CanadaPharmacies.com | $146.99 | — | Free | $146.99 |
 InhalersOnline.com | $188.66 | — | $0.00 | $565.98 |
 SPFPharmacy.com | $194.74 | — | $9.95 | $584.22 |
 CanadianPrescriptionDrugstore.com | $198.33 | — | $14.95 | $595.00 |
| InhalersOnline.com | $200.56 | — | $0.00 | $601.68 |
| SPFPharmacy.com | $204.96 | — | $9.95 | $204.96 |
| InhalersOnline.com | $210.71 | — | $0.00 | $210.71 |
| InhalersOnline.com | $215.94 | — | $0.00 | $215.94 |
Initial · 300 mg/500 mgfrom $488.57
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 LifeRxPharmacy.com | $162.86 | — | $14.95 | $488.57Lowest |
 OffShoreCheapMeds.com | $164.92 | — | $14.95 | $494.75 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Akynzeo.
Frequently asked questions
What's the cash price for Akynzeo (Akynzeo) in the US?
At the US pharmacies in our data, the lowest listed discount-card price for Akynzeo is around $697.16. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
How much does Akynzeo (Akynzeo) cost in Canada?
Canadian pharmacy listings in our data show Akynzeo priced from about $121.26 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.
Why does Akynzeo (Akynzeo) cost more in one country than the other?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. Check the comparison table above for the specific numbers on Akynzeo.
Is a generic version of Akynzeo available?
Generic and brand-name pricing for Akynzeo is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
Is Akynzeo covered by Medicare, and what would it cost?
Akynzeo is generally not covered under standard Medicare Part D prescription drug plans. However, it may be covered under Medicare Part B, particularly if the medication is administered via injection in a clinical setting, such as a hospital or doctor's office.
Is a generic equivalent of Akynzeo available?
Akynzeo is a brand-name medication. It is available in two formulations: an oral capsule containing netupitant and palonosetron, and an intravenous form containing fosnetupitant and palonosetron. As of now, there is no FDA-approved generic version of Akynzeo on the market.
What is Akynzeo and what is it used for?
Akynzeo is a prescription drug approved for adults to prevent nausea and vomiting that can occur after receiving chemotherapy for cancer. It is always used alongside dexamethasone, a corticosteroid. The medication is available as an oral capsule (netupitant/palonosetron) or an intravenous injection (fosnetupitant/palonosetron). These active ingredients work by blocking key pathways in the body and brain that cause nausea. The oral capsule is taken about one hour before chemotherapy, while the IV infusion is started 30 minutes prior.