US pharmacy pricing
Anusol-Hc Cost Without Insurance — US Pharmacy Price Guide
Lowest price found · US pharmacies
$12.41/fill
for Hydrocortisone (Perianal), across the pharmacies in our data
Discount card
$12.41
per fill
Lowest listed pharmacy price
Cost Plus Drugs
$0.666
per unit
Published price, no card needed
US pharmacy prices — 12 suppository
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Walmart Neighborhood Market | $12.41Lowest | $15.41 | $15.32 |
 Walmart Pharmacy | $12.41Lowest | $15.41 | $15.32 |
 Food Lion | $18.50 | $18.50 | $15.32 |
 Costco | $21.99 | $21.99 | $15.32 |
 CVS Pharmacy | $25.03 | $28.03 | $15.32 |
 Publix | $25.08 | $25.08 | $15.32 |
 Walgreens | $27.48 | $30.48 | $15.32 |
 Kroger Pharmacy | $48.99 | $51.99 | $15.32 |
 Harris Teeter Pharmacy | $48.99 | $51.99 | $15.32 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Frequently asked questions
What's the cash price for Hydrocortisone (Perianal) (Anusol-Hc) in the US?
Our most recent US pharmacy data shows a low of roughly $12.41 for Hydrocortisone (Perianal) with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
Is Hydrocortisone (Perianal) (Anusol-Hc) available through Cost Plus Drugs?
Yes — Cost Plus Drugs lists Hydrocortisone (Perianal) at roughly $0.666 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
Does Hydrocortisone (Perianal) have a generic equivalent?
Generic and brand-name pricing for Hydrocortisone (Perianal) is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
Is a generic version of Anusol-HC available?
Yes. Anusol-HC is the brand name for products containing 2.5% hydrocortisone acetate. Generic equivalents are widely available from multiple manufacturers. Generic hydrocortisone acetate cream is produced by companies such as Crown, Sebela, and Taro. Generic hydrocortisone acetate suppositories are available from manufacturers including Nucare and Paddock, among others.
What is Anusol-HC and what conditions does it treat?
Anusol-HC is a prescription corticosteroid medication formulated as a skin cream or a rectal suppository. The cream treats inflammatory skin conditions, reducing redness, swelling, and itching. The suppositories are used to manage symptoms of hemorrhoids, anal itching, and irritation from anal fissures. They are also sometimes prescribed to relieve discomfort from radiation-induced rectal injury or rectal sores related to ulcerative colitis. Its active ingredient, hydrocortisone acetate, works by inhibiting the body's inflammatory response. The cream is typically applied to the affected skin two to four times daily. A suppository is usually inserted twice daily (morning and night) for up to two weeks, unless otherwise directed by a doctor.
What are the potential side effects of using Anusol-HC?
Common side effects for the topical cream can include localized irritation, stinging, burning, itching, or a rash. With prolonged use, it may also cause acne, skin thinning, changes in skin color, hair follicle inflammation, or stretch marks. For the suppository, possible side effects are rectal burning, pain, bleeding, or the appearance of dark, tarry stools. Improper insertion can lead to damage of the rectal wall. This is not an exhaustive list. Consult your healthcare provider or pharmacist for more information about side effects and their management.