Full price comparison · US & Canada
Arthrotec (Diclofenac-Misoprostol) Rx Price Comparison: US vs Canada — Save Up to 20% in the US
Cheaper in the US
0%
lower price for Diclofenac-Misoprostol, based on the lowest comparable per-unit prices we found
US · discount card
$48.63
per fill
Lowest listed pharmacy price
US · Cost Plus Drugs
$0.343
per unit
Published price, no card needed
Canada
$0.430
per tablet
Lowest listed pharmacy price
US pharmacy prices — 75mg/0.2mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
| $48.63Lowest | $51.63 | $4.00 | |
| $72.50 | $75.50 | $4.00 | |
| $77.60 | $77.60 | $4.00 | |
| $80.48 | $83.48 | $4.00 | |
| $86.49 | $89.49 | $4.00 | |
| $86.49 | $89.49 | $4.00 | |
| $93.98 | $96.98 | $4.00 | |
| $93.98 | $96.98 | $4.00 | |
| $105.91 | $105.91 | $4.00 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
Initial · 50 mg/200 mcgfrom $64.27
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.940 | 180 | $0.00 | $168.60Lowest | |
| $1.07 | 60 | $0.00 | $64.27 | |
| $1.51 | 250 | $0.00 | $376.91 | |
| $1.62 | 250 | $9.95 | $405.93 |
Initial · 50 mg/200 mcgfrom $37.41
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.470 | 180 | Free | $85.03Lowest | |
| $0.530 | 180 | Free | $95.99 | |
| $0.620 | 60 | Free | $37.41 | |
| $0.670 | 180 | $14.95 | $119.80 | |
| $0.690 | 180 | $14.95 | $124.00 | |
| $0.690 | 180 | $14.95 | $124.08 | |
| $0.700 | 120 | $14.95 | $83.86 | |
| $0.720 | 120 | $14.95 | $86.86 | |
| $0.800 | 60 | Free | $47.99 |
Initial · 50 mcg/200 mcgfrom $124.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.690 | 180 | $14.95 | $124.00Lowest |
Initial · 75 mgfrom $347.94
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $1.39 | — | $0.00 | $347.94Lowest | |
| $1.55 | — | $0.00 | $386.60 |
Initial · 75 mg/200 mcgfrom $79.16
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $1.18 | 180 | $0.00 | $212.91Lowest | |
| $1.32 | 60 | $0.00 | $79.16 | |
| $1.77 | 250 | $0.00 | $443.34 | |
| $1.78 | 250 | $9.95 | $444.41 |
Initial · 75 mg/200 mcgfrom $45.06
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.600 | 180 | Free | $107.99Lowest | |
| $0.660 | 180 | Free | $118.99 | |
| $0.750 | 60 | Free | $45.06 | |
| $0.850 | 180 | $14.95 | $152.62 | |
| $0.870 | 180 | $14.95 | $156.00 | |
| $0.880 | 180 | $14.95 | $158.07 | |
| $0.890 | 120 | $14.95 | $106.83 | |
| $0.920 | 120 | $14.95 | $110.65 | |
| $0.930 | 60 | Free | $55.99 | |
| $1.19 | 180 | $0.00 | $215.00 | |
| $1.80 | 200 | $0.00 | $359.00 |
Initial · 75 mcg/200 mcgfrom $156.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.870 | 180 | $14.95 | $156.00Lowest |
Generic · 50 mg/0.2 mgfrom $65.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| RxOutreach.org | $0.720 | 90 | $0.00 | $65.00Lowest |
Generic · 50 mg/200 mcgfrom $47.09
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.430 | 200 | Free | $85.54Lowest | |
| $0.470 | 100 | Free | $47.09 | |
| $0.480 | 200 | Free | $96.99 | |
| $0.580 | 100 | Free | $57.99 |
Generic · 50 mcg/200 mcgfrom $128.89
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.520 | 250 | $9.95 | $128.89Lowest | |
| $0.560 | 250 | $0.00 | $140.43 |
Generic · 75 mg/0.2 mgfrom $130.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| RxOutreach.org | $0.720 | 180 | $0.00 | $130.00Lowest |
Generic · 75 mcg/200 mcgfrom $182.55
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.730 | 250 | $0.00 | $182.55Lowest |
Brand · 50 mg/0.2 mgfrom $65.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| RxOutreach.org | $0.720 | 90 | $0.00 | $65.00Lowest |
Brand · 50 mg/200 mcgfrom $47.09
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.430 | 200 | Free | $85.54Lowest | |
| $0.470 | 100 | Free | $47.09 | |
| $0.480 | 200 | Free | $96.99 | |
| $0.580 | 100 | Free | $57.99 |
Brand · 50 mcg/200 mcgfrom $128.89
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.520 | 250 | $9.95 | $128.89Lowest | |
| $0.560 | 250 | $0.00 | $140.43 |
Brand · 75 mg/0.2 mgfrom $130.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| RxOutreach.org | $0.720 | 180 | $0.00 | $130.00Lowest |
Brand · 75 mcg/200 mcgfrom $182.55
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.730 | 250 | $0.00 | $182.55Lowest |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Diclofenac-Misoprostol.
Frequently asked questions
How much does Diclofenac-Misoprostol (Arthrotec) cost without insurance?
Our most recent US pharmacy data shows a low of roughly $48.63 for Diclofenac-Misoprostol with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
Is Diclofenac-Misoprostol (Arthrotec) available through Cost Plus Drugs?
Yes — Cost Plus Drugs lists Diclofenac-Misoprostol at roughly $0.343 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
What do Canadian pharmacies charge for Diclofenac-Misoprostol (Arthrotec)?
We found Canadian pricing for Diclofenac-Misoprostol starting near $0.430 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.
Why is Diclofenac-Misoprostol (Arthrotec) priced differently in the US and Canada?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.
How much can I expect to pay for Arthrotec with my health insurance?
The copay for Arthrotec under an insurance plan depends entirely on the specifics of your coverage, such as your deductible and formulary tier. Contacting your insurer directly is the best way to get an accurate estimate. In some cases, using a pharmacy savings program might offer a price lower than your insurance copay, so it can be worthwhile to compare costs at your pharmacy before filling the prescription.
Is Arthrotec covered by Medicare, and what are the costs?
Arthrotec is typically not covered by standard Medicare Part D plans. However, patients have options to manage the expense. Using a pharmacy discount card could offer substantial savings on the retail price. Additionally, asking your doctor about the generic equivalent, diclofenac sodium and misoprostol, is a good strategy, as generic medications are more likely to be covered by Medicare and are generally more affordable.
Is a generic alternative to Arthrotec available?
Yes. Arthrotec is the brand-name product from Pfizer. Its generic equivalent is diclofenac sodium and misoprostol tablets, which contains the same active ingredients and is used for the same conditions.