Full price comparison · US & Canada

Astagraf Xl Prices — US Pharmacy Cost vs Canada — Save Up to 77% in the US

Brand availableRx requiredAvailable US & CanadacapsuleHealth Canada DIN 02175983

Cheaper in the US

0%

lower price for Tacrolimus Er, based on the lowest comparable per-unit prices we found

US · discount card

$618.80

per fill

Lowest listed pharmacy price

Lowest

US · Cost Plus Drugs

$0.073

per unit

Published price, no card needed

Canada

$0.320

per tablet

Lowest listed pharmacy price

Fetching live USD → CAD rate…

US pharmacy prices — 1mg

PharmacyDiscount-card priceRegular cash priceAverage retail
CVS Pharmacy$618.80Lowest$621.80$844.99
Walgreens$654.95$657.95$844.99
Publix$1,008.65$1,011.65$844.99
Kroger Pharmacy$1,527.15$1,530.15$844.99
Harris Teeter Pharmacy$1,527.15$1,530.15$844.99
Walmart Neighborhood Market$1,632.00$1,635.00$844.99
Walmart Pharmacy$1,632.00$1,635.00$844.99

"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.

Canadian pharmacy prices

Initial · 5 mgfrom $1,599.57
PharmacyPrice / tabletPack sizeShippingTotal
GoldStarMeds.com$16.00$0.00$1,599.57Lowest
1800RxOnline.com$17.77$0.00$1,777.30
CanadianPrescriptionDrugstore.com$19.63$14.95$1,963.00
Generic · 0.0003from $21.00
PharmacyPrice / tabletPack sizeShippingTotal
RxOutreach.org$0.350$0.00$21.00Lowest
GoldStarMeds.com$0.750$0.00$134.85
CanadianPharmacyAdvantage.com$0.790Free$158.72
1800RxOnline.com$0.830$0.00$149.83
CanadaPharmacies.com$0.850Free$169.99
CanadianPharmacyAdvantage.com$0.900Free$90.09
CanadianPrescriptionDrugstore.com$1.00$14.95$600.00
CanadaPharmacies.com$1.01Free$100.99
GoldStarMeds.com$1.14$0.00$684.52
1800RxOnline.com$1.27$0.00$760.58
CanadaPharmacyPro.com$1.27$14.95$763.33
InhalersOnline.com$1.36$0.00$162.84
CanadianPrescriptionDrugstore.com$1.44$14.95$143.75
GoldStarMeds.com$1.61$0.00$160.58
1800RxOnline.com$1.78$0.00$178.42
CanadaPharmacyPro.com$1.83$14.95$183.04
GoldStarMeds.com$1.84$0.00$55.22
InhalersOnline.com$1.90$0.00$190.04
1800RxOnline.com$2.05$0.00$61.36
SPFPharmacy.com$2.53$9.95$253.47
SPFPharmacy.com$4.20$9.95$126.00
InhalersOnline.com$4.23$0.00$42.31
InhalersOnline.com$4.50$0.00$134.99
Generic · 0.001from $21.00
PharmacyPrice / tabletPack sizeShippingTotal
RxOutreach.org$0.350$0.00$21.00Lowest
GoldStarMeds.com$0.750$0.00$134.85
CanadianPharmacyAdvantage.com$0.790Free$158.72
1800RxOnline.com$0.830$0.00$149.83
CanadaPharmacies.com$0.850Free$169.99
CanadianPharmacyAdvantage.com$0.900Free$90.09
CanadianPrescriptionDrugstore.com$1.00$14.95$600.00
CanadaPharmacies.com$1.01Free$100.99
GoldStarMeds.com$1.14$0.00$684.52
1800RxOnline.com$1.27$0.00$760.58
CanadaPharmacyPro.com$1.27$14.95$763.33
InhalersOnline.com$1.36$0.00$162.84
CanadianPrescriptionDrugstore.com$1.44$14.95$143.75
GoldStarMeds.com$1.61$0.00$160.58
1800RxOnline.com$1.78$0.00$178.42
CanadaPharmacyPro.com$1.83$14.95$183.04
GoldStarMeds.com$1.84$0.00$55.22
InhalersOnline.com$1.90$0.00$190.04
1800RxOnline.com$2.05$0.00$61.36
SPFPharmacy.com$2.53$9.95$253.47
SPFPharmacy.com$4.20$9.95$126.00
InhalersOnline.com$4.23$0.00$42.31
InhalersOnline.com$4.50$0.00$134.99
Generic · 0.03 %from $27.53
PharmacyPrice / tabletPack sizeShippingTotal
medsengage.com$27.53$14.95$27.53Lowest
medsengage.com$27.53$14.95$82.58
Generic · 0.1 %from $27.43
PharmacyPrice / tabletPack sizeShippingTotal
CanadianPrescriptionDrugstore.com$0.950$14.95$57.25Lowest
CanadianPharmacyAdvantage.com$0.960Free$96.21
CanadaPharmacies.com$1.07Free$106.99
LifeRxPharmacy.com$1.21$14.95$60.25
LifeRxPharmacy.com$1.33$14.95$39.77
CanadianPharmacyAdvantage.com$1.37Free$27.43
InhalersOnline.com$1.80$0.00$108.06
CanadaPharmacies.com$1.90Free$37.99
CanadaPharmacyPro.com$2.15$14.95$128.86
CanadaPharmacyPro.com$2.27$14.95$68.22
InhalersOnline.com$2.64$0.00$52.76
Generic · 0.1 %/10 %from $56.62
PharmacyPrice / tabletPack sizeShippingTotal
medsengage.com$15.73$14.95$78.64Lowest
medsengage.com$18.87$14.95$56.62
Generic · 0.25 mgfrom $27.23
PharmacyPrice / tabletPack sizeShippingTotal
GoldStarMeds.com$0.320$0.00$57.83Lowest
1800RxOnline.com$0.360$0.00$64.26
GoldStarMeds.com$0.910$0.00$27.23
1800RxOnline.com$1.01$0.00$30.26
Generic · 0.5 mgfrom $21.00
PharmacyPrice / tabletPack sizeShippingTotal
RxOutreach.org$0.350$0.00$21.00Lowest
GoldStarMeds.com$0.720$0.00$86.05
1800RxOnline.com$0.800$0.00$95.61
LifeRxPharmacy.com$0.85090$14.95$76.55
LifeRxPharmacy.com$0.94060$14.95$56.14
InhalersOnline.com$0.970$0.00$116.60
InhalersOnline.com$1.16$0.00$69.61
GoldStarMeds.com$1.25$0.00$37.44
1800RxOnline.com$1.39$0.00$41.60
InhalersOnline.com$1.42$0.00$142.15
CanadianPharmacyAdvantage.com$1.49Free$148.66
CanadaPharmacies.com$1.60Free$159.99
SPFPharmacy.com$2.12$9.95$211.58
Generic · 2 mgfrom $94.44
PharmacyPrice / tabletPack sizeShippingTotal
GoldStarMeds.com$1.35$0.00$242.54Lowest
1800RxOnline.com$1.50$0.00$269.49
GoldStarMeds.com$3.15$0.00$94.44
1800RxOnline.com$3.50$0.00$104.93
Generic · 3 mgfrom $288.75
PharmacyPrice / tabletPack sizeShippingTotal
InhalersOnline.com$8.78$0.00$789.99Lowest
SPFPharmacy.com$8.93$9.95$803.25
SPFPharmacy.com$9.63$9.95$288.75
InhalersOnline.com$9.67$0.00$289.99
Generic · 5 mgfrom $55.00
PharmacyPrice / tabletPack sizeShippingTotal
RxOutreach.org$0.920$0.00$55.00Lowest
CanadianPharmacyAdvantage.com$4.46Free$222.78
InhalersOnline.com$4.50$0.00$450.02
CanadaPharmacies.com$4.68Free$233.99
LifeRxPharmacy.com$5.8390$14.95$524.67
LifeRxPharmacy.com$6.4160$14.95$384.76
InhalersOnline.com$10.40100$0.00$1,039.99
SPFPharmacy.com$11.49100$9.95$1,148.70
InhalersOnline.com$14.83$0.00$444.99
SPFPharmacy.com$15.05$9.95$451.50
Brand · 0.0003from $21.00
PharmacyPrice / tabletPack sizeShippingTotal
RxOutreach.org$0.350$0.00$21.00Lowest
GoldStarMeds.com$0.750$0.00$134.85
CanadianPharmacyAdvantage.com$0.790Free$158.72
1800RxOnline.com$0.830$0.00$149.83
CanadaPharmacies.com$0.850Free$169.99
CanadianPharmacyAdvantage.com$0.900Free$90.09
CanadianPrescriptionDrugstore.com$1.00$14.95$600.00
CanadaPharmacies.com$1.01Free$100.99
GoldStarMeds.com$1.14$0.00$684.52
1800RxOnline.com$1.27$0.00$760.58
CanadaPharmacyPro.com$1.27$14.95$763.33
InhalersOnline.com$1.36$0.00$162.84
CanadianPrescriptionDrugstore.com$1.44$14.95$143.75
GoldStarMeds.com$1.61$0.00$160.58
1800RxOnline.com$1.78$0.00$178.42
CanadaPharmacyPro.com$1.83$14.95$183.04
GoldStarMeds.com$1.84$0.00$55.22
InhalersOnline.com$1.90$0.00$190.04
1800RxOnline.com$2.05$0.00$61.36
SPFPharmacy.com$2.53$9.95$253.47
SPFPharmacy.com$4.20$9.95$126.00
InhalersOnline.com$4.23$0.00$42.31
InhalersOnline.com$4.50$0.00$134.99
Brand · 0.001from $21.00
PharmacyPrice / tabletPack sizeShippingTotal
RxOutreach.org$0.350$0.00$21.00Lowest
GoldStarMeds.com$0.750$0.00$134.85
CanadianPharmacyAdvantage.com$0.790Free$158.72
1800RxOnline.com$0.830$0.00$149.83
CanadaPharmacies.com$0.850Free$169.99
CanadianPharmacyAdvantage.com$0.900Free$90.09
CanadianPrescriptionDrugstore.com$1.00$14.95$600.00
CanadaPharmacies.com$1.01Free$100.99
GoldStarMeds.com$1.14$0.00$684.52
1800RxOnline.com$1.27$0.00$760.58
CanadaPharmacyPro.com$1.27$14.95$763.33
InhalersOnline.com$1.36$0.00$162.84
CanadianPrescriptionDrugstore.com$1.44$14.95$143.75
GoldStarMeds.com$1.61$0.00$160.58
1800RxOnline.com$1.78$0.00$178.42
CanadaPharmacyPro.com$1.83$14.95$183.04
GoldStarMeds.com$1.84$0.00$55.22
InhalersOnline.com$1.90$0.00$190.04
1800RxOnline.com$2.05$0.00$61.36
SPFPharmacy.com$2.53$9.95$253.47
SPFPharmacy.com$4.20$9.95$126.00
InhalersOnline.com$4.23$0.00$42.31
InhalersOnline.com$4.50$0.00$134.99
Brand · 0.03 %from $27.53
PharmacyPrice / tabletPack sizeShippingTotal
medsengage.com$27.53$14.95$27.53Lowest
medsengage.com$27.53$14.95$82.58
Brand · 0.1 %from $27.43
PharmacyPrice / tabletPack sizeShippingTotal
CanadianPrescriptionDrugstore.com$0.950$14.95$57.25Lowest
CanadianPharmacyAdvantage.com$0.960Free$96.21
CanadaPharmacies.com$1.07Free$106.99
LifeRxPharmacy.com$1.21$14.95$60.25
LifeRxPharmacy.com$1.33$14.95$39.77
CanadianPharmacyAdvantage.com$1.37Free$27.43
InhalersOnline.com$1.80$0.00$108.06
CanadaPharmacies.com$1.90Free$37.99
CanadaPharmacyPro.com$2.15$14.95$128.86
CanadaPharmacyPro.com$2.27$14.95$68.22
InhalersOnline.com$2.64$0.00$52.76
Brand · 0.1 %/10 %from $56.62
PharmacyPrice / tabletPack sizeShippingTotal
medsengage.com$15.73$14.95$78.64Lowest
medsengage.com$18.87$14.95$56.62
Brand · 0.25 mgfrom $27.23
PharmacyPrice / tabletPack sizeShippingTotal
GoldStarMeds.com$0.320$0.00$57.83Lowest
1800RxOnline.com$0.360$0.00$64.26
GoldStarMeds.com$0.910$0.00$27.23
1800RxOnline.com$1.01$0.00$30.26
Brand · 0.5 mgfrom $21.00
PharmacyPrice / tabletPack sizeShippingTotal
RxOutreach.org$0.350$0.00$21.00Lowest
GoldStarMeds.com$0.720$0.00$86.05
1800RxOnline.com$0.800$0.00$95.61
LifeRxPharmacy.com$0.85090$14.95$76.55
LifeRxPharmacy.com$0.94060$14.95$56.14
InhalersOnline.com$0.970$0.00$116.60
InhalersOnline.com$1.16$0.00$69.61
GoldStarMeds.com$1.25$0.00$37.44
1800RxOnline.com$1.39$0.00$41.60
InhalersOnline.com$1.42$0.00$142.15
CanadianPharmacyAdvantage.com$1.49Free$148.66
CanadaPharmacies.com$1.60Free$159.99
SPFPharmacy.com$2.12$9.95$211.58
Brand · 2 mgfrom $94.44
PharmacyPrice / tabletPack sizeShippingTotal
GoldStarMeds.com$1.35$0.00$242.54Lowest
1800RxOnline.com$1.50$0.00$269.49
GoldStarMeds.com$3.15$0.00$94.44
1800RxOnline.com$3.50$0.00$104.93
Brand · 3 mgfrom $288.75
PharmacyPrice / tabletPack sizeShippingTotal
InhalersOnline.com$8.78$0.00$789.99Lowest
SPFPharmacy.com$8.93$9.95$803.25
SPFPharmacy.com$9.63$9.95$288.75
InhalersOnline.com$9.67$0.00$289.99
Brand · 5 mgfrom $55.00
PharmacyPrice / tabletPack sizeShippingTotal
RxOutreach.org$0.920$0.00$55.00Lowest
CanadianPharmacyAdvantage.com$4.46Free$222.78
InhalersOnline.com$4.50$0.00$450.02
CanadaPharmacies.com$4.68Free$233.99
LifeRxPharmacy.com$5.8390$14.95$524.67
LifeRxPharmacy.com$6.4160$14.95$384.76
InhalersOnline.com$10.40100$0.00$1,039.99
SPFPharmacy.com$11.49100$9.95$1,148.70
InhalersOnline.com$14.83$0.00$444.99
SPFPharmacy.com$15.05$9.95$451.50

Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.

Interchangeable forms

Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Tacrolimus Er.

Other brand names
Astagraf
Generic clinical forms
24 HR tacrolimus 0.5 MG Extended Release Oral Capsule

Frequently asked questions

Is Tacrolimus Er (Astagraf Xl) expensive if I don't have insurance?

Our most recent US pharmacy data shows a low of roughly $618.80 for Tacrolimus Er with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Is Tacrolimus Er (Astagraf Xl) available through Cost Plus Drugs?

Yes — Cost Plus Drugs lists Tacrolimus Er at roughly $0.073 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

What do Canadian pharmacies charge for Tacrolimus Er (Astagraf Xl)?

We found Canadian pricing for Tacrolimus Er starting near $0.320 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.

Why is Tacrolimus Er (Astagraf Xl) priced differently in the US and Canada?

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.

What is the typical cost of Astagraf XL without insurance coverage?

The cash price for Astagraf XL at most retail pharmacies can be substantial. For a supply of 60 capsules (5mg, extended-release), the retail price is often quoted at a high figure. Patients without insurance can explore pharmacy savings programs or discount cards, which may offer a significantly lower price at participating pharmacies.

How much will Astagraf XL cost with my insurance plan?

Your out-of-pocket cost for Astagraf XL with insurance depends entirely on the specifics of your plan, including your deductible, copay, or coinsurance. It can be helpful to compare your insurance copay against the price available through pharmacy discount programs, as the latter may sometimes offer a lower final cost.

Is Astagraf XL covered by Medicare, and what are the potential costs?

Astagraf XL is often considered a necessary part of post-transplant care. While it may not typically be covered under a standard Medicare Part D prescription drug plan, it can be covered as a medical benefit under Medicare Part B following a transplant surgery. If Part B does not apply, coverage may fall under Part D. Costs vary based on your Medicare plan details and coverage phase. For those without Medicare coverage, investigating other savings options can help manage the prescription's expense.