US pharmacy pricing
Where to Find the Cheapest Caplyta Price
Lowest price found · US pharmacies
$1,669.07/fill
for Caplyta, across the pharmacies in our data
US pharmacy prices — 42mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $1,669.07Lowest | $1,672.07 | $1.22 |
 Harris Teeter Pharmacy | $1,669.07Lowest | $1,672.07 | $1.22 |
 CVS Pharmacy | $1,751.75 | $1,754.75 | $1.22 |
 Walgreens | $1,757.00 | $1,760.00 | $1.22 |
 Publix | $1,769.03 | $1,772.03 | $1.22 |
 Walmart Neighborhood Market | $1,798.85 | $1,801.85 | $1.22 |
 Walmart Pharmacy | $1,798.85 | $1,801.85 | $1.22 |
 Costco | $1,809.12 | $1,812.12 | $1.22 |
 Food Lion | $1,839.35 | $1,839.35 | $1.22 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Caplyta.
Frequently asked questions
Is Caplyta (Caplyta) expensive if I don't have insurance?
Our most recent US pharmacy data shows a low of roughly $1,669.07 for Caplyta with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
Does Caplyta have a generic equivalent?
Generic and brand-name pricing for Caplyta is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
What is Caplyta, and what should patients know before taking it?
Caplyta (lumateperone) is an atypical antipsychotic approved to treat schizophrenia and depressive episodes associated with bipolar I or II disorder in adults. It comes in oral capsules (10.5 mg, 21 mg, and 42 mg) taken once daily, with or without food. Important safety information includes a black box warning against use in elderly patients with dementia-related psychosis due to an increased risk of death, and a warning about the potential for suicidal thoughts and behaviors, particularly in younger patients. Caplyta can cause drowsiness, dizziness, and problems with body temperature regulation. Patients should avoid alcohol, grapefruit juice, and activities like driving until they know how the medication affects them. Discuss all medical conditions, including pregnancy, breastfeeding, fertility concerns, and a full list of other medications with your healthcare provider before starting treatment.
What are the potential side effects associated with Caplyta?
Common side effects include nausea, dry mouth, sleepiness, and dizziness. Caplyta carries a black box warning, the FDA's strongest alert, stating it should not be used to treat dementia-related psychosis in elderly patients due to an increased risk of death. The warning also highlights the potential for increased suicidal thoughts and behaviors, particularly in children and young adults. Other serious but less common side effects may include neuroleptic malignant syndrome (a life-threatening reaction with high fever and muscle stiffness), tardive dyskinesia (involuntary movements), metabolic changes (like weight gain and increased blood sugar), low white blood cell counts, a sudden drop in blood pressure upon standing (which can lead to falls), seizures, cognitive impairment, swallowing difficulties, and problems with body temperature control. Seek immediate medical attention for signs of an allergic reaction (hives, swelling, difficulty breathing) or symptoms of neuroleptic malignant syndrome.
Is weight gain a common side effect of Caplyta treatment?
As with all antipsychotic medications, weight gain is a possible side effect of Caplyta. However, clinical studies suggest Caplyta may carry a relatively lower risk of significant weight gain compared to some other drugs in its class. Your doctor will typically monitor your weight at the start of therapy and at regular intervals throughout your treatment.