Full price comparison · US & Canada
How Much Does Depakote Cost? — Save Up to 90% in the US
Cheaper in the US
0%
lower price for Divalproex Sodium Er, based on the lowest comparable per-unit prices we found
US · discount card
$21.20
per fill
Lowest listed pharmacy price
US · Cost Plus Drugs
$0.030
per unit
Published price, no card needed
Canada
$0.310
per tablet
Lowest listed pharmacy price
US pharmacy prices — 250mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
| $21.20Lowest | $21.20 | $11.99 | |
| $22.16 | $25.16 | $11.99 | |
| $22.16 | $25.16 | $11.99 | |
| $22.98 | $25.98 | $11.99 | |
| $25.25 | $25.25 | $11.99 | |
| $26.73 | $29.73 | $11.99 | |
| $26.77 | $29.77 | $11.99 | |
| $26.77 | $29.77 | $11.99 | |
| $28.56 | $28.56 | $11.99 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
Initial · 500 mgfrom $42.85
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.420 | 150 | $14.95 | $63.00Lowest | |
| $0.500 | 150 | Free | $74.61 | |
| $0.530 | 120 | $14.95 | $63.04 | |
| $0.550 | 90 | $14.95 | $49.68 | |
| $0.570 | 150 | Free | $85.99 | |
| $0.820 | — | $0.00 | $123.20 | |
| $1.01 | 180 | $14.95 | $181.00 | |
| $1.06 | 90 | $14.95 | $95.82 | |
| $2.86 | — | $0.00 | $42.85 |
Generic · 125 mgfrom $32.39
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.450 | 90 | $14.95 | $40.49Lowest | |
| $0.480 | 90 | $14.95 | $43.02 | |
| $0.540 | 60 | $14.95 | $32.39 | |
| $0.570 | 60 | $14.95 | $34.41 |
Generic · 500 mgfrom $32.06
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.310 | 150 | $14.95 | $46.00Lowest | |
| $0.340 | 120 | $14.95 | $40.48 | |
| $0.490 | 90 | $14.95 | $43.71 | |
| $0.500 | 150 | Free | $74.85 | |
| $0.530 | 60 | $14.95 | $32.06 | |
| $0.570 | 150 | Free | $85.99 | |
| $0.670 | 100 | $14.95 | $67.00 |
Generic · 750 mgfrom $53.95
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.750 | 90 | $14.95 | $67.44Lowest | |
| $0.800 | 90 | $14.95 | $71.66 | |
| $0.900 | 60 | $14.95 | $53.95 | |
| $0.960 | 60 | $14.95 | $57.32 |
Generic · 1000 mgfrom $55.65
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.770 | 90 | $14.95 | $69.56Lowest | |
| $0.820 | 90 | $14.95 | $73.91 | |
| $0.930 | 60 | $14.95 | $55.65 | |
| $0.990 | 60 | $14.95 | $59.13 |
Brand · 125 mgfrom $32.39
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.450 | 90 | $14.95 | $40.49Lowest | |
| $0.480 | 90 | $14.95 | $43.02 | |
| $0.540 | 60 | $14.95 | $32.39 | |
| $0.570 | 60 | $14.95 | $34.41 |
Brand · 500 mgfrom $32.06
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.310 | 150 | $14.95 | $46.00Lowest | |
| $0.340 | 120 | $14.95 | $40.48 | |
| $0.490 | 90 | $14.95 | $43.71 | |
| $0.500 | 150 | Free | $74.85 | |
| $0.530 | 60 | $14.95 | $32.06 | |
| $0.570 | 150 | Free | $85.99 | |
| $0.670 | 100 | $14.95 | $67.00 |
Brand · 750 mgfrom $53.95
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.750 | 90 | $14.95 | $67.44Lowest | |
| $0.800 | 90 | $14.95 | $71.66 | |
| $0.900 | 60 | $14.95 | $53.95 | |
| $0.960 | 60 | $14.95 | $57.32 |
Brand · 1000 mgfrom $55.65
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.770 | 90 | $14.95 | $69.56Lowest | |
| $0.820 | 90 | $14.95 | $73.91 | |
| $0.930 | 60 | $14.95 | $55.65 | |
| $0.990 | 60 | $14.95 | $59.13 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Divalproex Sodium Er.
Frequently asked questions
Is Divalproex Sodium Er (Depakote) expensive if I don't have insurance?
At the US pharmacies in our data, the lowest listed discount-card price for Divalproex Sodium Er is around $21.20. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Can I buy Divalproex Sodium Er (Depakote) at a Cost Plus Drugs price?
Yes — Cost Plus Drugs lists Divalproex Sodium Er at roughly $0.030 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
How much does Divalproex Sodium Er (Depakote) cost in Canada?
Canadian pharmacy listings in our data show Divalproex Sodium Er priced from about $0.310 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.
Why does Divalproex Sodium Er (Depakote) cost more in one country than the other?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.
Is a generic form of Depakote ER available?
Yes. Depakote ER is the brand-name version of divalproex sodium extended-release, manufactured by AbbVie Inc. The generic equivalent is available.
What is Depakote ER used to treat?
Depakote ER is an extended-release anticonvulsant from the fatty acid derivative drug class. It is primarily prescribed to treat various types of seizure disorders, manage manic episodes in bipolar disorder, and help prevent migraine headaches. The medication works by helping to restore the balance of certain neurotransmitters in the brain. It is crucial to discuss your full medical history with your doctor before starting this medication, as it is contraindicated in people with certain liver diseases, urea cycle disorders, or specific genetic conditions like Alpers' disease. Special precautions are necessary for individuals with a history of depression, mental illness, or mitochondrial disorders. Due to a high risk of serious birth defects and potential long-term effects on a child's development, the use of Depakote ER during pregnancy requires careful management and should never be started or stopped without direct medical supervision.
What side effects are associated with Depakote ER?
Common side effects of Depakote ER can include nausea, vomiting, stomach discomfort, diarrhea, headache, dizziness, weakness, tremors, coordination problems, blurred vision, and changes in appetite or weight. A serious and potentially fatal risk is liver failure, which is of particular concern for children under two years old and individuals with certain genetic mitochondrial disorders. This is not a complete list of possible adverse effects. Always consult your healthcare provider for advice on managing any side effects you experience.