Depo-Provera (Medroxyprogesterone Acetate) Rx Price Comparison: US vs Canada — Save Up to 79% in the US

Our most recent US pharmacy data shows a low of roughly $31.31 for Medroxyprogesterone Acetate with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Yes — Cost Plus Drugs lists Medroxyprogesterone Acetate at roughly $0.065 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

We found Canadian pricing for Medroxyprogesterone Acetate starting near $0.310 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.

Yes. The active ingredient in Depo-Provera is medroxyprogesterone. Generic medroxyprogesterone acetate injections are manufactured by several companies, including Nucare, Teva, and Sun Pharmaceutical, and are consistently less expensive than the brand-name product. It's crucial to understand that this medication is always administered by a healthcare professional in a clinical setting. Therefore, the choice between the brand-name and generic injection is typically made by the prescribing physician and the healthcare facility providing the service.

Depo-Provera is a brand-name prescription injection containing the hormone medroxyprogesterone. It is primarily used to treat certain cancers that are sensitive to estrogen, specifically inoperable or metastatic endometrial cancer (cancer of the uterine lining) and kidney cancer. By reducing estrogen levels in the body, it can help slow the growth of these cancers. Medroxyprogesterone is also approved under different brand names (Depo-Provera CI, Depo Sub-Q Provera 104) as a long-acting contraceptive injection. Additionally, it is sometimes prescribed off-label for conditions like endometriosis or abnormal uterine bleeding. The injection is given by a healthcare provider, typically on a weekly schedule for cancer treatment, with the dose determined by the prescribing physician.

Common side effects of Depo-Provera include reactions at the injection site (pain, redness, or a lump), menstrual cycle changes, weight gain, bloating, nausea, headache, dizziness, fatigue, breast tenderness, acne, and hair loss. Some people may experience mood changes, such as depression or nervousness. Less common but more serious potential side effects include liver problems, blood clots, and high calcium levels. Allergic reactions, though rare, can occur and may present as rash, hives, or difficulty breathing, which require immediate medical attention. This is not an exhaustive list. Discuss any concerns about potential side effects with your doctor.