Full price comparison · US & Canada
How Much Does Desvenlafaxine Er Cost? — Save Up to 67% in the US
Cheaper in the US
0%
lower price for Desvenlafaxine Er, based on the lowest comparable per-unit prices we found
US · discount card
$143.92
per fill
Lowest listed pharmacy price
US · Cost Plus Drugs
$0.177
per unit
Published price, no card needed
Canada
$0.530
per tablet
Lowest listed pharmacy price
US pharmacy prices — 50mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $143.92Lowest | $146.92 | $275.01 |
 Harris Teeter Pharmacy | $143.92Lowest | $146.92 | $275.01 |
 Walgreens | $152.64 | $155.64 | $275.01 |
 Publix | $154.76 | $157.76 | $275.01 |
 Walmart Neighborhood Market | $154.88 | $157.88 | $275.01 |
 Walmart Pharmacy | $154.88 | $157.88 | $275.01 |
 Food Lion | $156.02 | $156.02 | $275.01 |
 CVS Pharmacy | $162.46 | $165.46 | $275.01 |
 Costco | $167.56 | $167.56 | $275.01 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
Initial · 25 mgfrom $30.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| RxOutreach.org | $0.560 | 90 | $0.00 | $50.00Lowest |
 InhalersOnline.com | $0.760 | 100 | $0.00 | $75.68 |
| RxOutreach.org | $1.00 | 30 | $0.00 | $30.00 |
Initial · 100 mgfrom $30.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.530 | 90 | $14.95 | $47.29Lowest | |
| $0.550 | 60 | $14.95 | $33.28 | |
| RxOutreach.org | $0.560 | 90 | $0.00 | $50.00 |
 LifeRxPharmacy.com | $0.570 | 90 | $14.95 | $51.69 |
 OffShoreCheapMeds.com | $0.580 | 90 | $14.95 | $51.91 |
| LifeRxPharmacy.com | $0.610 | 60 | $14.95 | $36.38 |
| OffShoreCheapMeds.com | $0.610 | 60 | $14.95 | $36.53 |
 CanadianPrescriptionDrugstore.com | $0.630 | 90 | $14.95 | $57.00 |
 CanadianPharmacyAdvantage.com | $0.710 | 84 | Free | $59.34 |
 CanadaPharmacies.com | $0.820 | 84 | Free | $68.99 |
| RxOutreach.org | $1.00 | 30 | $0.00 | $30.00 |
 BuyLowDrugs.com | $1.01 | 168 | $0.00 | $170.00 |
 GoldStarMeds.com | $1.04 | — | $0.00 | $174.90 |
 CanadaPharmacyPro.com | $1.05 | 168 | $14.95 | $177.09 |
| InhalersOnline.com | $1.09 | 100 | $0.00 | $109.08 |
 1800RxOnline.com | $1.16 | — | $0.00 | $194.33 |
| CanadianPharmacyAdvantage.com | $1.23 | 28 | Free | $34.36 |
| InhalersOnline.com | $1.30 | 50 | $0.00 | $64.86 |
| GoldStarMeds.com | $1.31 | 30 | $0.00 | $39.16 |
| GoldStarMeds.com | $1.42 | — | $0.00 | $119.16 |
| 1800RxOnline.com | $1.45 | 30 | $0.00 | $43.51 |
| InhalersOnline.com | $1.48 | 84 | $0.00 | $123.99 |
| CanadaPharmacyPro.com | $1.53 | 84 | $14.95 | $128.57 |
| BuyLowDrugs.com | $1.57 | 84 | $0.00 | $132.00 |
| CanadaPharmacies.com | $1.57 | 28 | Free | $43.99 |
| 1800RxOnline.com | $1.58 | — | $0.00 | $132.40 |
| InhalersOnline.com | $2.44 | 28 | $0.00 | $68.30 |
 SPFPharmacy.com | $3.11 | 100 | $9.95 | $310.80 |
| GoldStarMeds.com | $3.67 | — | $0.00 | $110.11 |
| 1800RxOnline.com | $4.08 | — | $0.00 | $122.34 |
Generic · 100 mgfrom $35.81
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| CanadianPharmacyAdvantage.com | $0.750 | 84 | Free | $63.11Lowest |
| CanadaPharmacies.com | $0.880 | 84 | Free | $73.99 |
| CanadianPrescriptionDrugstore.com | $1.00 | 90 | $14.95 | $90.00 |
| GoldStarMeds.com | $1.14 | — | $0.00 | $382.47 |
| CanadaPharmacyPro.com | $1.22 | 336 | $14.95 | $410.41 |
| 1800RxOnline.com | $1.26 | — | $0.00 | $424.97 |
| CanadianPharmacyAdvantage.com | $1.28 | 28 | Free | $35.81 |
| GoldStarMeds.com | $1.29 | — | $0.00 | $216.35 |
| 1800RxOnline.com | $1.43 | — | $0.00 | $240.39 |
| CanadaPharmacyPro.com | $1.51 | 168 | $14.95 | $253.32 |
| CanadaPharmacies.com | $1.64 | 28 | Free | $45.99 |
| BuyLowDrugs.com | $2.36 | 168 | $0.00 | $397.00 |
| InhalersOnline.com | $2.43 | 84 | $0.00 | $203.73 |
| BuyLowDrugs.com | $2.68 | 84 | $0.00 | $225.00 |
| InhalersOnline.com | $2.96 | 28 | $0.00 | $82.85 |
| SPFPharmacy.com | $3.55 | 90 | $9.95 | $319.62 |
| InhalersOnline.com | $3.61 | 90 | $0.00 | $325.32 |
| SPFPharmacy.com | $3.94 | 30 | $9.95 | $118.24 |
| InhalersOnline.com | $4.34 | 30 | $0.00 | $130.06 |
| GoldStarMeds.com | $4.36 | — | $0.00 | $130.77 |
| 1800RxOnline.com | $4.84 | — | $0.00 | $145.30 |
Brand · 100 mgfrom $35.81
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| CanadianPharmacyAdvantage.com | $0.750 | 84 | Free | $63.11Lowest |
| CanadaPharmacies.com | $0.880 | 84 | Free | $73.99 |
| CanadianPrescriptionDrugstore.com | $1.00 | 90 | $14.95 | $90.00 |
| GoldStarMeds.com | $1.14 | — | $0.00 | $382.47 |
| CanadaPharmacyPro.com | $1.22 | 336 | $14.95 | $410.41 |
| 1800RxOnline.com | $1.26 | — | $0.00 | $424.97 |
| CanadianPharmacyAdvantage.com | $1.28 | 28 | Free | $35.81 |
| GoldStarMeds.com | $1.29 | — | $0.00 | $216.35 |
| 1800RxOnline.com | $1.43 | — | $0.00 | $240.39 |
| CanadaPharmacyPro.com | $1.51 | 168 | $14.95 | $253.32 |
| CanadaPharmacies.com | $1.64 | 28 | Free | $45.99 |
| BuyLowDrugs.com | $2.36 | 168 | $0.00 | $397.00 |
| InhalersOnline.com | $2.43 | 84 | $0.00 | $203.73 |
| BuyLowDrugs.com | $2.68 | 84 | $0.00 | $225.00 |
| InhalersOnline.com | $2.96 | 28 | $0.00 | $82.85 |
| SPFPharmacy.com | $3.55 | 90 | $9.95 | $319.62 |
| InhalersOnline.com | $3.61 | 90 | $0.00 | $325.32 |
| SPFPharmacy.com | $3.94 | 30 | $9.95 | $118.24 |
| InhalersOnline.com | $4.34 | 30 | $0.00 | $130.06 |
| GoldStarMeds.com | $4.36 | — | $0.00 | $130.77 |
| 1800RxOnline.com | $4.84 | — | $0.00 | $145.30 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Desvenlafaxine Er.
Frequently asked questions
How much does Desvenlafaxine Er (Desvenlafaxine Er) cost without insurance?
At the US pharmacies in our data, the lowest listed discount-card price for Desvenlafaxine Er is around $143.92. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Can I buy Desvenlafaxine Er (Desvenlafaxine Er) at a Cost Plus Drugs price?
Yes — Cost Plus Drugs lists Desvenlafaxine Er at roughly $0.177 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
How much does Desvenlafaxine Er (Desvenlafaxine Er) cost in Canada?
Canadian pharmacy listings in our data show Desvenlafaxine Er priced from about $0.530 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.
Why does Desvenlafaxine Er (Desvenlafaxine Er) cost more in one country than the other?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.
How much will I pay for Desvenlafaxine Succinate ER with my insurance plan?
Your copay with insurance varies based on your specific plan's formulary and the prescribed dosage. To ensure you get the best price, ask your pharmacist to compare your insurance copay against the price available with a prescription savings card. In some cases, the discounted cash price may be lower than your insurance copayment.
Is Desvenlafaxine Succinate ER covered by Medicare, and what are the costs?
Desvenlafaxine Succinate ER is often covered under Medicare Part D and Medicare Advantage plans. However, coverage and out-of-pocket costs can vary significantly depending on your specific plan. For Medicare beneficiaries, using a pharmacy discount program can sometimes offer additional savings, potentially reducing the cash price for a 30-tablet supply of the generic medication. It's advisable to compare options with your pharmacist.
What is the brand-name version of Desvenlafaxine Succinate ER?
Desvenlafaxine Succinate ER is the generic name for the extended-release drug. Its brand-name counterpart is Khedezla. Generic versions are produced by several manufacturers, such as Alembic, West Ward, and Mylan. It's a good practice to inquire about available savings options, like manufacturer coupons, before filling your prescription.