Full price comparison · US & Canada
Durezol Prices — US Pharmacy Cost vs Canada — Save Up to 90% in Canada
Cheaper in Canada
0%
lower price for Difluprednate, based on the lowest comparable per-unit prices we found
US · discount card
$37.39
per fill
Lowest listed pharmacy price
US · Cost Plus Drugs
$15.01
per unit
Published price, no card needed
Canada
$1.51
per tablet
Lowest listed pharmacy price
US pharmacy prices — 5ml of 0.05%
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 CVS Pharmacy | $37.39Lowest | $40.39 | $49.46 |
 Publix | $55.03 | $55.03 | $49.46 |
 Walmart Neighborhood Market | $58.56 | $61.56 | $49.46 |
 Walmart Pharmacy | $58.56 | $61.56 | $49.46 |
 Walgreens | $69.28 | $72.28 | $49.46 |
 Food Lion | $101.45 | $101.45 | $49.46 |
 Kroger Pharmacy | $115.54 | $118.54 | $49.46 |
 Harris Teeter Pharmacy | $115.54 | $118.54 | $49.46 |
 Costco | $119.99 | $119.99 | $49.46 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 CanadianPharmacyAdvantage.com | $1.51 | — | Free | $22.68Lowest |
 CanadaPharmacies.com | $2.27 | — | Free | $33.99 |
 CanadianPrescriptionDrugstore.com | $2.27 | — | $14.95 | $34.00 |
| $2.63 | — | $14.95 | $39.49 | |
 OffShoreCheapMeds.com | $2.67 | — | $14.95 | $40.11 |
| $2.78 | — | $14.95 | $27.79 | |
| OffShoreCheapMeds.com | $2.82 | — | $14.95 | $28.23 |
 LifeRxPharmacy.com | $2.86 | — | $14.95 | $42.84 |
| CanadianPharmacyAdvantage.com | $2.88 | — | Free | $14.38 |
| LifeRxPharmacy.com | $3.02 | — | $14.95 | $30.15 |
 InhalersOnline.com | $3.76 | — | $0.00 | $56.46 |
 CanadaPharmacyPro.com | $4.50 | — | $14.95 | $135.06 |
| CanadaPharmacyPro.com | $4.77 | — | $14.95 | $71.50 |
| CanadaPharmacies.com | $5.00 | — | Free | $24.99 |
| InhalersOnline.com | $7.17 | — | $0.00 | $35.86 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Frequently asked questions
How much does Difluprednate (Durezol) cost without insurance?
At the US pharmacies in our data, the lowest listed discount-card price for Difluprednate is around $37.39. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Can I buy Difluprednate (Durezol) at a Cost Plus Drugs price?
Yes — Cost Plus Drugs lists Difluprednate at roughly $15.01 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
How much does Difluprednate (Durezol) cost in Canada?
Canadian pharmacy listings in our data show Difluprednate priced from about $1.51 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.
Why does Difluprednate (Durezol) cost more in one country than the other?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the Canadian price coming in lower — but that isn't true for every drug, so it's worth checking each medication individually rather than assuming.
What is the brand name for the drug Difluprednate?
Difluprednate is available under the brand name Durezol. While its price is similar to the generic, brand-name Durezol may be less frequently covered by insurance plans.
How can I save money on a Difluprednate prescription?
Several strategies can help reduce the cost. Using a prescription discount card at the pharmacy is one straightforward method. It's also wise to compare prices at different local pharmacies, as costs can vary. For those who qualify, assistance programs like Medicaid, Medicare Part D Extra Help, or medication programs through 340B clinics or hospitals can provide significant savings.
Are there lower-cost alternatives to Difluprednate?
For reducing eye inflammation, ophthalmologists have several options. Less expensive corticosteroid eye drops, such as dexamethasone or prednisolone, are often first-line treatments. However, difluprednate is a more potent steroid typically reserved for specific needs, such as inflammation following cataract surgery, so these cheaper alternatives may not always be suitable. In some cases, non-steroidal anti-inflammatory eye drops (NSAIDs) like ketorolac or diclofenac might be considered, especially if a patient is experiencing increased eye pressure from steroid use.