Full price comparison · US & Canada

How Much Does Enbrel Cost?

Brand availableRx requiredAvailable US & CanadasyringeHealth Canada DIN 02242903

Price comparison

See both prices

We don't have a directly comparable per-unit price for Enbrel yet — the full breakdown is below.

US · discount card

$7,709.52

per fill

Lowest listed pharmacy price

Lowest

Canada

$623.75

per tablet

Lowest listed pharmacy price

Fetching live USD → CAD rate…

US pharmacy prices — 1ml of 50mg/ml

PharmacyDiscount-card priceRegular cash priceAverage retail
Kroger Pharmacy$7,709.52Lowest$7,712.52$1,092.39
Harris Teeter Pharmacy$7,709.52Lowest$7,712.52$1,092.39
Walgreens$8,122.42$8,125.42$1,092.39
Publix$8,175.06$8,178.06$1,092.39
Costco$8,377.63$8,380.63$1,092.39

"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.

Canadian pharmacy prices

PharmacyPrice / tabletPack sizeShippingTotal
OverTheBorderMeds.com$623.75$14.99$2,495.00Lowest

Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.

Interchangeable forms

Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Enbrel.

Generic clinical forms
etanercept 25 MG/ML Injectable Solution

Frequently asked questions

How much does Enbrel (Enbrel) cost without insurance?

Our most recent US pharmacy data shows a low of roughly $7,709.52 for Enbrel with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

What do Canadian pharmacies charge for Enbrel (Enbrel)?

We found Canadian pricing for Enbrel starting near $623.75 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.

Why is Enbrel (Enbrel) priced differently in the US and Canada?

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. Check the comparison table above for the specific numbers on Enbrel.

Does Enbrel have a generic equivalent?

Generic and brand-name pricing for Enbrel is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.

How does insurance coverage affect the price of Enbrel?

The final cost of Enbrel with insurance depends on your specific plan's formulary, copayment, coinsurance rates, and deductible status. While insurance often provides substantial coverage, patients may still have significant out-of-pocket expenses. It's advisable to contact your insurance provider directly for precise cost details. In some cases, comparing your insurance copay against prices available through pharmacy savings programs may be beneficial.

Is Enbrel covered under Medicare plans, and what are the potential costs?

Medicare coverage for Enbrel is not uniform and depends on the specific Part D or Medicare Advantage plan, its formulary, and the beneficiary's coverage phase (e.g., deductible, initial coverage, or coverage gap). To understand your potential copay or coinsurance, you should review your plan's drug list. For situations where Medicare coverage is limited or unavailable, exploring other savings options like manufacturer patient assistance programs may help reduce costs.

Is a generic form of Enbrel available?

No, a generic version of Enbrel is not currently on the market. Enbrel is a brand-name biologic drug whose patent protections are expected to last until around 2029. After this date, biosimilar versions—which are similar but not identical to the original biologic—may become available.