US pharmacy pricing
Exparel Cost Without Insurance — US Pharmacy Price Guide
Lowest price found · US pharmacies
$411.41/fill
for Exparel, across the pharmacies in our data
US pharmacy prices — 20ml of 1.3%
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $411.41Lowest | $414.41 | $915.45 |
 Harris Teeter Pharmacy | $411.41Lowest | $414.41 | $915.45 |
 Walgreens | $433.25 | $436.25 | $915.45 |
 Publix | $437.02 | $440.02 | $915.45 |
 Walmart Neighborhood Market | $442.06 | $445.06 | $915.45 |
 Walmart Pharmacy | $442.06 | $445.06 | $915.45 |
 Costco | $444.06 | $447.06 | $915.45 |
 CVS Pharmacy | $445.49 | $448.49 | $915.45 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Exparel.
Frequently asked questions
What's the cash price for Exparel (Exparel) in the US?
At the US pharmacies in our data, the lowest listed discount-card price for Exparel is around $411.41. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Is a generic version of Exparel available?
Generic and brand-name pricing for Exparel is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
How much does Exparel cost with health insurance?
Your out-of-pocket cost for Exparel with insurance depends on your specific plan's formulary, coverage tier, and benefit design. To determine your exact copay or coinsurance, ask your pharmacist to run a test claim. For those with high copays or no coverage, a pharmacy savings card may provide an alternative way to access lower prices.
Is a generic version of Exparel available?
No. Exparel is a branded product manufactured by Pacira BioSciences, Inc., and there is currently no FDA-approved generic equivalent on the market.
What is Exparel and how is it used?
Exparel is a non-opioid, injectable medication used to control pain after surgery, which can aid recovery. Its active ingredient, bupivacaine, is a local anesthetic that blocks nerve signals in a specific area of the body. Unlike opioids that affect the whole system, Exparel is administered directly into the surgical site via an injection in a hospital or surgical center. The dosage is carefully determined by your doctor based on your medical condition, other medications, age, and weight. Its effects can be long-lasting; numbness or reduced movement in the treated area may persist for up to several days. It's important to inform your doctor if you have liver disease, heart conditions, or a history of seizures, as closer monitoring may be needed. Report any joint pain or stiffness to your healthcare provider.