Full price comparison · US & Canada

How Much Does Trintellix Cost?

Brand availableRx requiredAvailable US & CanadatabletHealth Canada DIN 02432919

Price comparison

See both prices

We don't have a directly comparable per-unit price for yet — the full breakdown is below.

US · discount card

$489.04

per fill

Lowest listed pharmacy price

Lowest

Canada

$0.750

per tablet

Lowest listed pharmacy price

Fetching live USD → CAD rate…

US pharmacy prices — 20mg

PharmacyDiscount-card priceRegular cash priceAverage retail
Walmart Neighborhood Market$489.04Lowest$492.04$42.91
Walmart Pharmacy$489.04Lowest$492.04$42.91
Kroger Pharmacy$491.07$494.07$42.91
Harris Teeter Pharmacy$491.07$494.07$42.91
Publix$499.96$502.96$29.00
CVS Pharmacy$509.84$512.84$42.91
Costco$509.92$512.92$42.91
Walgreens$522.26$525.26$29.00
Food Lion$558.66$558.66$40.91

"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.

Canadian pharmacy prices

Initial · 10 mgfrom $38.48
PharmacyPrice / tabletPack sizeShippingTotal
1800RxOnline.com$0.85084$0.00$71.46Lowest
1800RxOnline.com$1.3728$0.00$38.48
Initial · 20 mgfrom $41.78
PharmacyPrice / tabletPack sizeShippingTotal
1800RxOnline.com$0.97084$0.00$81.35Lowest
1800RxOnline.com$1.4928$0.00$41.78
Generic · 5from $82.99
PharmacyPrice / tabletPack sizeShippingTotal
InhalersOnline.com$0.830100$0.00$82.99Lowest
Generic · 10 mgfrom $67.50
PharmacyPrice / tabletPack sizeShippingTotal
CanadianPrescriptionDrugstore.com$0.75090$14.95$67.50Lowest
CanadianPharmacyAdvantage.com$0.760100Free$76.05
CanadaPharmacies.com$0.860100Free$85.99
InhalersOnline.com$1.20100$0.00$119.99
BuyLowDrugs.com$1.26100$0.00$126.00
SPFPharmacy.com$3.00100$9.95$300.00
InhalersOnline.com$3.20100$0.00$319.99
Generic · 20 mgfrom $104.00
PharmacyPrice / tabletPack sizeShippingTotal
CanadianPrescriptionDrugstore.com$1.04100$14.95$104.00Lowest
InhalersOnline.com$1.05100$0.00$104.90
CanadianPharmacyAdvantage.com$1.11100Free$111.05
BuyLowDrugs.com$1.16100$0.00$116.00
CanadaPharmacies.com$1.23100Free$122.99
SPFPharmacy.com$3.30100$9.95$330.00
InhalersOnline.com$3.50100$0.00$349.99
Generic · mgfrom $82.99
PharmacyPrice / tabletPack sizeShippingTotal
InhalersOnline.com$0.830100$0.00$82.99Lowest
Brand · 5from $82.99
PharmacyPrice / tabletPack sizeShippingTotal
InhalersOnline.com$0.830100$0.00$82.99Lowest
Brand · 10 mgfrom $67.50
PharmacyPrice / tabletPack sizeShippingTotal
CanadianPrescriptionDrugstore.com$0.75090$14.95$67.50Lowest
CanadianPharmacyAdvantage.com$0.760100Free$76.05
CanadaPharmacies.com$0.860100Free$85.99
InhalersOnline.com$1.20100$0.00$119.99
BuyLowDrugs.com$1.26100$0.00$126.00
SPFPharmacy.com$3.00100$9.95$300.00
InhalersOnline.com$3.20100$0.00$319.99
Brand · 20 mgfrom $104.00
PharmacyPrice / tabletPack sizeShippingTotal
CanadianPrescriptionDrugstore.com$1.04100$14.95$104.00Lowest
InhalersOnline.com$1.05100$0.00$104.90
CanadianPharmacyAdvantage.com$1.11100Free$111.05
BuyLowDrugs.com$1.16100$0.00$116.00
CanadaPharmacies.com$1.23100Free$122.99
SPFPharmacy.com$3.30100$9.95$330.00
InhalersOnline.com$3.50100$0.00$349.99
Brand · mgfrom $82.99
PharmacyPrice / tabletPack sizeShippingTotal
InhalersOnline.com$0.830100$0.00$82.99Lowest

Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.

Interchangeable forms

Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as .

Other brand names
Trintellix
Generic clinical forms
vortioxetine 10 MG Oral Tablet

Frequently asked questions

What's the cash price for (Trintellix) in the US?

At the US pharmacies in our data, the lowest listed discount-card price for is around $489.04. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.

How much does (Trintellix) cost in Canada?

Canadian pharmacy listings in our data show priced from about $0.750 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.

Why does (Trintellix) cost more in one country than the other?

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. Check the comparison table above for the specific numbers on .

Is a generic version of available?

Generic and brand-name pricing for is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.

Is Trintellix typically covered under Medicare plans?

Trintellix is generally covered under Medicare Part D prescription drug plans and Medicare Advantage plans that include drug coverage. However, your out-of-pocket cost will vary based on your plan's specific formulary, deductible, and copayment or coinsurance structure. Contact your Medicare drug plan directly for precise cost details. If your Medicare coverage leaves you with a high cost share, you may find additional savings by using a prescription discount card. Comparing prices at different pharmacies using such a tool can help identify the most affordable option for your prescription.

Is a generic version of Trintellix available?

No, a generic version of Trintellix is not currently available. Trintellix is a brand-name drug whose active ingredient is vortioxetine. It was originally marketed under the name Brintellix, but the FDA requested a name change to Trintellix to prevent potential confusion with the heart medication Brilinta.

What are some strategies to lower the cost of Trintellix?

Several approaches can help manage the cost of Trintellix. A primary method is to use a free pharmacy savings card, which can significantly reduce the cash price. Other potential strategies include asking your doctor for free samples (though this is a short-term solution), checking if you qualify for the manufacturer's coupon program (typically for those with commercial, non-government insurance), and applying for patient assistance programs based on income. You can also shop around at different pharmacies for the best price, see if you qualify for Medicare Extra Help, use pre-tax funds from an FSA or HSA if available, and discuss with your healthcare provider whether a clinically appropriate alternative medication might be more affordable.