Glipizide Prices — US Pharmacy Cost vs Canada — Save Up to 84% in the US

At the US pharmacies in our data, the lowest listed discount-card price for Glipizide Er is around $15.99. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.

Yes — Cost Plus Drugs lists Glipizide Er at roughly $0.013 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

Canadian pharmacy listings in our data show Glipizide Er priced from about $0.080 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.

Glipizide ER is the generic form of the medication. The extended-release brand-name product, manufactured by Pfizer, is called Glucotrol XL.

Glipizide ER is an extended-release oral medication used to treat Type 2 diabetes. It helps control blood sugar by stimulating the pancreas to produce more insulin, the hormone that allows cells to take in glucose from the bloodstream. This medication is intended to be used alongside foundational lifestyle changes like a healthy diet and regular exercise, which are crucial for effective long-term blood sugar management.

The most serious potential side effect of Glipizide ER is hypoglycemia, or low blood sugar, which can cause symptoms like dizziness, shakiness, rapid heartbeat, headache, and confusion. More common, less severe side effects may include digestive issues such as nausea, diarrhea, gas, and loss of appetite, as well as headache, dizziness, and weight gain. Mood changes and rare allergic reactions (e.g., hives, swelling, difficulty breathing) have also been reported. Always discuss any concerns about side effects with your doctor or pharmacist.