Where to Find the Cheapest Heplisav-B Price

At the US pharmacies in our data, the lowest listed discount-card price for Heplisav-B is around $150.99. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.

Generic and brand-name pricing for Heplisav-B is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.

The cost of Heplisav-B with insurance depends on your specific plan's formulary, copay, and deductible structure. You should contact your insurance provider directly to confirm coverage and your expected out-of-pocket expense. If your plan does not cover Heplisav-B or imposes a high copay, it can be worthwhile to compare the pharmacy's cash price using a discount card against your insurance copay to find the most affordable option. This comparison strategy also applies to those with Medicare or Medicaid if the vaccine is not covered under their benefit.

No. Heplisav-B is currently only available as a brand-name vaccine from its manufacturer, Dynavax Technologies. A generic (biosimilar) equivalent is not on the market, so cost-saving options are limited to insurance coverage, manufacturer patient assistance programs, or pharmacy discount programs.