Eplerenone Prices — US Pharmacy Cost vs Canada — Save Up to 72% in the US

At the US pharmacies in our data, the lowest listed discount-card price for Eplerenone is around $21.80. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.

Yes — Cost Plus Drugs lists Eplerenone at roughly $0.141 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

Canadian pharmacy listings in our data show Eplerenone priced from about $0.500 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.

Eplerenone is the generic name for the medication sold under the brand name Inspra. Generic versions are manufactured by several companies, including Apotex Corp. and Mylan Pharmaceuticals, Inc.

Eplerenone is a prescription medication classified as a selective aldosterone blocker. It is approved to treat high blood pressure (hypertension) and to improve survival in patients with congestive heart failure following a heart attack. The drug works by inhibiting the hormone aldosterone, leading to reduced sodium and water retention, which lowers blood pressure and decreases the heart's workload. It is crucial to inform your doctor of your full medical history, especially regarding kidney disease, diabetes, or high potassium levels, and to disclose all other medications and supplements you are taking, as eplerenone can interact with drugs like certain antifungals, antibiotics, HIV protease inhibitors, and potassium supplements. Always take this medication exactly as prescribed by your healthcare provider, with or without food.

Common side effects of eplerenone can include elevated potassium levels in the blood (hyperkalemia), kidney function changes, headache, and dizziness. More serious side effects that require immediate medical attention include symptoms like severe diarrhea or vomiting, difficulty breathing, fast or irregular heartbeats, and noticeable swelling in the feet or lower legs. It is important to have your potassium levels and kidney function monitored regularly while taking this medication.