US pharmacy pricing
Kuvan Cost Without Insurance — US Pharmacy Price Guide
Lowest price found · US pharmacies
$2,180.79/fill
for Sapropterin Dihydrochloride, across the pharmacies in our data
Discount card
$2,180.79
per fill
Lowest listed pharmacy price
Cost Plus Drugs
$8.35
per unit
Published price, no card needed
US pharmacy prices — 100mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Walgreens | $2,180.79Lowest | $2,183.79 | $2,352.45 |
 Publix | $3,345.09 | $3,348.09 | $2,352.45 |
 Kroger Pharmacy | $4,897.08 | $4,900.08 | $2,352.45 |
 Harris Teeter Pharmacy | $4,897.08 | $4,900.08 | $2,352.45 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Sapropterin Dihydrochloride.
Frequently asked questions
Is Sapropterin Dihydrochloride (Kuvan) expensive if I don't have insurance?
At the US pharmacies in our data, the lowest listed discount-card price for Sapropterin Dihydrochloride is around $2,180.79. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Can I buy Sapropterin Dihydrochloride (Kuvan) at a Cost Plus Drugs price?
Yes — Cost Plus Drugs lists Sapropterin Dihydrochloride at roughly $8.35 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
Is a generic version of Sapropterin Dihydrochloride available?
Generic and brand-name pricing for Sapropterin Dihydrochloride is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
How much can I expect to pay for Kuvan with my health insurance plan?
Your out-of-pocket cost for Kuvan with insurance depends on your specific plan's formulary, deductible, and copay or coinsurance structure. Some plans cover it, while others may not. The best course of action is to contact your insurance provider directly for details on your coverage and estimated costs. If your plan does not cover Kuvan, or if your copay is high, you may want to explore other savings options, such as pharmacy discount programs, to lower your cost. Patients with Medicare or Medicaid should check their plan's coverage and can also ask their pharmacist about available savings programs if their prescription is not covered.