How Much Does Femara Cost? — Save Up to 91% in the US

Our most recent US pharmacy data shows a low of roughly $5.63 for Letrozole with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Yes — Cost Plus Drugs lists Letrozole at roughly $0.072 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

We found Canadian pricing for Letrozole starting near $0.800 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.

Yes, Femara is a brand-name drug. Its generic equivalent is called letrozole, which contains the same active ingredient and is approved for the same uses, typically at a much lower cost.

Femara (letrozole) is an FDA-approved oral medication used to treat hormone receptor-positive breast cancer in postmenopausal women. It belongs to a class of drugs called aromatase inhibitors, which work by lowering estrogen levels in the body. This reduction in estrogen can slow or stop the growth of certain breast cancer cells. The medication is taken once daily as a tablet, with or without food, at a dose determined by your doctor based on your medical condition. It is crucial not to exceed the prescribed dose. Because letrozole can pose risks during pregnancy, women who are pregnant or may become pregnant should not use this medication. Furthermore, pregnant women should avoid handling the tablets or breathing in dust from them, as the drug can be absorbed through the skin and lungs.

Common side effects of Femara (letrozole) include hot flashes, joint or muscle pain, fatigue, increased sweating, hair thinning, nausea, dizziness, diarrhea, and difficulty sleeping. While these are often manageable, you should discuss persistent symptoms with your doctor. Although rare, letrozole can increase the risk of serious conditions like blood clots, stroke, or heart attack. Seek immediate medical attention for symptoms such as sudden shortness of breath, chest pain, confusion, coughing up blood, severe headache, vision changes, slurred speech, fainting, or swelling in a limb. This is not a complete list of side effects; your healthcare provider can give you full information on the risks and benefits of treatment.