Lomotil Prices at US Pharmacies

Our most recent US pharmacy data shows a low of roughly $14.11 for Diphenoxylate-Atropine with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Generic and brand-name pricing for Diphenoxylate-Atropine is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.

Lomotil may be covered under many Medicare Part D and Medicare Advantage prescription drug plans. The specific copay or coinsurance amount will depend on your plan's formulary and coverage phase. For precise cost information, you should contact your plan provider directly. If you have limited coverage or are in a coverage gap, using a prescription discount coupon at participating pharmacies can provide an alternative way to access savings on this medication.

Yes. Lomotil is the brand name for the combination drug diphenoxylate and atropine. Generic diphenoxylate and atropine is widely available and is manufactured by several companies, including Mylan, Mayne Pharma, and Leading Pharma, among others.

Lomotil is a prescription combination drug containing diphenoxylate and atropine, used alongside fluid and electrolyte therapy to treat severe diarrhea. Diphenoxylate is an opioid that acts on the intestines to slow down muscle contractions and motility. This allows more time for water and nutrients to be absorbed, reducing stool frequency and liquidity. Because diphenoxylate has abuse potential, a small amount of atropine is added to produce unpleasant effects if the medication is taken in excessive doses, acting as a deterrent. The standard tablet contains 2.5 mg of diphenoxylate and 0.025 mg of atropine sulfate. The typical adult dosage is two tablets taken four times daily. Symptom improvement usually occurs within 48 hours; if no improvement is seen after 10 days, consult your doctor. Important safety notes: Lomotil is not appropriate for diarrhea caused by certain bacterial infections and should be used cautiously in patients with liver or kidney disease. Always discuss your full medical history and other medications with your doctor before starting treatment.