Hyzaar Prices — US Pharmacy Cost vs Canada — Save Up to 92% in the US

At the US pharmacies in our data, the lowest listed discount-card price for Losartan Potassium-Hctz is around $10.00. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.

Yes — Cost Plus Drugs lists Losartan Potassium-Hctz at roughly $0.022 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

Canadian pharmacy listings in our data show Losartan Potassium-Hctz priced from about $0.280 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.

Yes, a generic version of Hyzaar is available. The brand-name product is manufactured by Organon. Its generic equivalent is called losartan-hydrochlorothiazide, which is produced by multiple pharmaceutical manufacturers, offering a typically more affordable option.

Hyzaar is a combination prescription medication containing two active ingredients: losartan (an angiotensin II receptor blocker) and hydrochlorothiazide (a diuretic, or 'water pill'). It is primarily used to treat high blood pressure. In some patients with hypertension and left ventricular hypertrophy (LVH), it may be prescribed to help reduce the risk of stroke. It is important to note that clinical studies suggest it may not be effective for reducing stroke risk in Black patients with these conditions. Hyzaar is not approved for use in children under 18. Important safety information includes: Do not take Hyzaar if you are allergic to losartan, hydrochlorothiazide, or sulfa drugs. Inform your doctor of all medical conditions, especially glaucoma, diabetes, gout, asthma, kidney disease, or difficulty urinating. Hyzaar can cause serious harm or death to an unborn baby if taken during the second or third trimester of pregnancy; notify your doctor immediately if you become pregnant. It is also not recommended while breastfeeding. Provide your healthcare provider with a complete list of all medications, including prescriptions, over-the-counter drugs, and supplements, particularly potassium supplements or diabetes medications containing aliskiren. Take Hyzaar exactly as prescribed. Your dose may be adjusted based on your response. Contact your doctor if you experience vomiting, diarrhea, or excessive sweating, as these can lead to dehydration and low blood pressure. Your doctor will advise how often to monitor your blood pressure. Hydrochlorothiazide can increase sensitivity to sunlight and the risk of skin cancer; limit sun exposure, wear protective clothing, and use sunscreen. Avoid potassium supplements or salt substitutes unless approved by your doctor. Limit alcohol, as it can intensify blood pressure-lowering effects and side effects. Stay well-hydrated, especially during exercise or in hot weather.

Common side effects of Hyzaar include dizziness, symptoms of a cold or upper respiratory infection, cough, nasal congestion, increased sun sensitivity, nausea, vomiting, indigestion, and back pain. More serious, but less common, side effects can include severe low blood pressure, kidney or liver problems, pancreatitis, or new or worsening symptoms of lupus. A severe allergic reaction (manifesting as hives, difficulty breathing, or swelling of the face, lips, throat, or tongue) requires immediate emergency medical attention. This is not an exhaustive list. For comprehensive information on risks and side effects, consult the official medication guide, speak with your doctor or pharmacist, or visit the FDA's website to report adverse events.