Full price comparison · US & Canada
Mestinon Prices — US Pharmacy Cost vs Canada — Save Up to 20% in the US
Cheaper in the US
0%
lower price for Pyridostigmine Bromide, based on the lowest comparable per-unit prices we found
US · discount card
$26.54
per fill
Lowest listed pharmacy price
US · Cost Plus Drugs
$0.376
per unit
Published price, no card needed
Canada
$0.470
per tablet
Lowest listed pharmacy price
US pharmacy prices — 60mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Walmart Neighborhood Market | $26.54Lowest | $29.54 | $9.64 |
 Walmart Pharmacy | $26.54Lowest | $29.54 | $9.64 |
 CVS Pharmacy | $28.00 | $31.00 | $9.64 |
 Kroger Pharmacy | $34.59 | $37.59 | $9.64 |
 Harris Teeter Pharmacy | $34.59 | $37.59 | $9.64 |
 Costco | $34.99 | $34.99 | $9.64 |
 Food Lion | $35.90 | $35.90 | $9.64 |
 Walgreens | $36.03 | $39.03 | $9.64 |
 Publix | $42.28 | $42.28 | $9.64 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
Initial · Defaultfrom $130.05
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 GoldStarMeds.com | $1.97 | — | $0.00 | $196.69Lowest |
 1800RxOnline.com | $2.19 | — | $0.00 | $218.54 |
| GoldStarMeds.com | $2.60 | — | $0.00 | $130.05 |
| 1800RxOnline.com | $2.89 | — | $0.00 | $144.50 |
Generic · 60 mgfrom $30.47
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 LifeRxPharmacy.com | $0.470 | 90 | $14.95 | $42.09Lowest |
 CanadianPrescriptionDrugstore.com | $0.500 | 1000 | $14.95 | $495.00 |
 OffShoreCheapMeds.com | $0.500 | 90 | $14.95 | $45.26 |
| LifeRxPharmacy.com | $0.510 | 60 | $14.95 | $30.87 |
| $0.540 | 90 | $14.95 | $48.38 | |
| OffShoreCheapMeds.com | $0.550 | 60 | $14.95 | $33.19 |
| $0.590 | 60 | $14.95 | $35.48 | |
| GoldStarMeds.com | $1.02 | 30 | $0.00 | $30.47 |
| 1800RxOnline.com | $1.13 | 30 | $0.00 | $33.85 |
Brand · 60 mgfrom $30.47
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| LifeRxPharmacy.com | $0.470 | 90 | $14.95 | $42.09Lowest |
| CanadianPrescriptionDrugstore.com | $0.500 | 1000 | $14.95 | $495.00 |
| OffShoreCheapMeds.com | $0.500 | 90 | $14.95 | $45.26 |
| LifeRxPharmacy.com | $0.510 | 60 | $14.95 | $30.87 |
| $0.540 | 90 | $14.95 | $48.38 | |
| OffShoreCheapMeds.com | $0.550 | 60 | $14.95 | $33.19 |
| $0.590 | 60 | $14.95 | $35.48 | |
| GoldStarMeds.com | $1.02 | 30 | $0.00 | $30.47 |
| 1800RxOnline.com | $1.13 | 30 | $0.00 | $33.85 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Pyridostigmine Bromide.
Frequently asked questions
How much does Pyridostigmine Bromide (Mestinon) cost without insurance?
At the US pharmacies in our data, the lowest listed discount-card price for Pyridostigmine Bromide is around $26.54. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Can I buy Pyridostigmine Bromide (Mestinon) at a Cost Plus Drugs price?
Yes — Cost Plus Drugs lists Pyridostigmine Bromide at roughly $0.376 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
How much does Pyridostigmine Bromide (Mestinon) cost in Canada?
Canadian pharmacy listings in our data show Pyridostigmine Bromide priced from about $0.470 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.
Why does Pyridostigmine Bromide (Mestinon) cost more in one country than the other?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.
How much will I pay for Mestinon with my insurance plan?
Your out-of-pocket cost for Mestinon with insurance depends on your specific plan's formulary and copay structure. It can be beneficial to ask your pharmacist to compare your insurance copay against the price available through a prescription savings program, as the latter may sometimes offer a lower price.
Is Mestinon covered by Medicare, and what is the typical cost?
Most Medicare Part D and Medicare Advantage prescription drug plans typically cover the generic form of Mestinon, pyridostigmine. Your exact cost will depend on your plan's specific coverage tier and deductible status. Medicare beneficiaries can also explore using a pharmacy discount card, which may, in some cases, provide a price lower than the plan's copay.
Is a generic version of Mestinon available?
Yes. Mestinon is the brand name for the medication pyridostigmine bromide. The generic equivalent, pyridostigmine bromide, is widely available and is manufactured by several companies, including Amneal Pharmaceuticals, Elysium Pharmaceuticals, and Alvogen.