US pharmacy pricing
Where to Find the Cheapest Nexium Price
Lowest price found · US pharmacies
$20.89/fill
for Esomeprazole Magnesium, across the pharmacies in our data
Discount card
$20.89
per fill
Lowest listed pharmacy price
Cost Plus Drugs
$0.024
per unit
Published price, no card needed
US pharmacy prices — 40mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $20.89Lowest | $23.89 | $18.82 |
 Harris Teeter Pharmacy | $20.89Lowest | $23.89 | $18.82 |
 Food Lion | $22.11 | $22.11 | $18.82 |
 Walmart Neighborhood Market | $25.85 | $28.85 | $18.82 |
 Walmart Pharmacy | $25.85 | $28.85 | $18.82 |
 Publix | $28.83 | $28.83 | $18.82 |
 CVS Pharmacy | $34.51 | $37.51 | $18.82 |
 Walgreens | $34.59 | $37.59 | $18.82 |
 Costco | $45.97 | $45.97 | $18.82 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Esomeprazole Magnesium.
Frequently asked questions
How much does Esomeprazole Magnesium (Nexium) cost without insurance?
At the US pharmacies in our data, the lowest listed discount-card price for Esomeprazole Magnesium is around $20.89. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Can I buy Esomeprazole Magnesium (Nexium) at a Cost Plus Drugs price?
Yes — Cost Plus Drugs lists Esomeprazole Magnesium at roughly $0.024 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
Is a generic version of Esomeprazole Magnesium available?
Generic and brand-name pricing for Esomeprazole Magnesium is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
Is Nexium covered by Medicare plans, and what is the cost?
Coverage for Nexium under Medicare depends on the specific Part D or Advantage plan. You should review your plan's formulary to see if Nexium or its generic is included and what the associated copay would be. If your plan does not cover it or the out-of-pocket cost is high, using a pharmacy discount card for either the brand or generic medication at your local pharmacy is an option to explore for lower prices.
Is a generic equivalent of Nexium available?
Yes, the generic name for Nexium is esomeprazole. Generic medications typically cost less and are commonly covered by insurance plans. If your health plan does not cover brand-name Nexium, you can ask your pharmacist if generic esomeprazole is a covered alternative. If neither is covered, using a pharmacy discount card can help manage the out-of-pocket expense for the generic version.
What is Nexium and what does it treat?
Nexium is a proton pump inhibitor (PPI). It works by blocking an enzyme in the stomach responsible for acid production, thereby providing relief from heartburn and acid-related damage. While stomach acid is necessary, excess acid can lead to problems like acid reflux, heartburn, erosive esophagitis, and stomach lining erosion. Prescription-strength Nexium is used to treat specific conditions, including certain stomach ulcers and infections like H. pylori.