US pharmacy pricing
Nucynta Prices at US Pharmacies
Lowest price found · US pharmacies
$251.30/fill
for Tapentadol Hcl, across the pharmacies in our data
US pharmacy prices — 50mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 CVS Pharmacy | $251.30Lowest | $251.30 | $26.99 |
 Publix | $477.36 | $477.36 | $26.99 |
 Walgreens | $545.41 | $545.41 | $26.99 |
 Kroger Pharmacy | $737.01 | $737.01 | $26.99 |
 Harris Teeter Pharmacy | $737.01 | $737.01 | $26.99 |
 Food Lion | $740.01 | $740.01 | $26.99 |
 Costco | $742.01 | $742.01 | $26.99 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Tapentadol Hcl.
Frequently asked questions
What's the cash price for Tapentadol Hcl (Nucynta) in the US?
Our most recent US pharmacy data shows a low of roughly $251.30 for Tapentadol Hcl with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
Does Tapentadol Hcl have a generic equivalent?
Generic and brand-name pricing for Tapentadol Hcl is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
What should I expect to pay for Nucynta if I have health insurance?
Your out-of-pocket cost with insurance depends entirely on your specific plan's formulary and coverage rules. Some plans may not cover brand-name opioids like Nucynta or may require a high copayment. It's best to contact your insurance provider directly for details on your coverage and any potential alternatives. If your copay is high, you might ask your pharmacist if other savings options are applicable.
Is Nucynta typically covered under Medicare Part D plans?
Nucynta is often not covered by standard Medicare Part D prescription drug plans due to its status as a brand-name opioid. If you have Medicare, you should check with your plan administrator to confirm coverage and cost. Your doctor or pharmacist can also discuss whether a covered alternative medication might be appropriate for your condition.
Is a generic form of tapentadol available?
No. Nucynta is a brand-name medication containing the active ingredient tapentadol. A generic equivalent is not currently available in the U.S. market, which is a factor in its higher cost.