US pharmacy pricing
Nucynta Er Prices at US Pharmacies
Lowest price found · US pharmacies
$1,460.10/fill
for Nucynta Er, across the pharmacies in our data
US pharmacy prices — 100mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 CVS Pharmacy | $1,460.10Lowest | $1,460.10 | $103.38 |
 Food Lion | $1,513.51 | $1,513.51 | $103.38 |
 Walgreens | $1,521.12 | $1,521.12 | $103.38 |
 Publix | $1,531.22 | $1,531.22 | $103.38 |
 Kroger Pharmacy | $1,545.94 | $1,545.94 | $103.38 |
 Harris Teeter Pharmacy | $1,545.94 | $1,545.94 | $103.38 |
 Costco | $1,636.84 | $1,636.84 | $103.38 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Nucynta Er.
Frequently asked questions
What's the cash price for Nucynta Er (Nucynta Er) in the US?
Our most recent US pharmacy data shows a low of roughly $1,460.10 for Nucynta Er with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
Does Nucynta Er have a generic equivalent?
Generic and brand-name pricing for Nucynta Er is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
What determines the cost of Nucynta ER with insurance?
The out-of-pocket cost with insurance is highly variable and depends on your specific plan's formulary, tier placement, and benefit structure. Even with coverage, you will likely be responsible for a copayment or coinsurance. It is essential to contact your insurance provider directly for the most accurate and current information regarding your coverage and expected costs for this medication.
Is a generic version of Nucynta ER available?
Nucynta ER is only available as a brand-name medication containing tapentadol. A generic equivalent is not currently on the market. The patent protecting Nucynta ER is expected to expire in 2025, after which generic versions may become available.
What is Nucynta ER used for, and how does it work?
Nucynta ER is an extended-release opioid analgesic approved by the FDA for managing severe, persistent pain that requires continuous, long-term treatment. It is also indicated for neuropathic pain associated with diabetic peripheral neuropathy. Its active ingredient, tapentadol, works by binding to opioid receptors in the brain, thereby altering pain perception. The extended-release formulation is designed for twice-daily dosing. Treatment typically begins at a low dose, which your doctor may adjust gradually to achieve effective pain control while minimizing side effects. It can be taken with or without food, strictly as prescribed.