Klayesta (Nystatin) Rx Price Comparison: US vs Canada — Save Up to 60% in Canada

Our most recent US pharmacy data shows a low of roughly $21.23 for Nystatin with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Yes — Cost Plus Drugs lists Nystatin at roughly $0.200 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

We found Canadian pricing for Nystatin starting near $0.080 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the Canadian price coming in lower — but that isn't true for every drug, so it's worth checking each medication individually rather than assuming.

Insurance coverage for brand-name Klayesta varies widely by plan. Many insurance plans prefer the generic version, nystatin. If Klayesta is covered, your specific copay or coinsurance will depend on your plan's formulary and benefit structure.

Coverage for Klayesta under Medicare Part D plans is not universal. Some plans may cover it, while others may only cover the generic nystatin. Out-of-pocket costs depend on your plan's deductible and coverage phase. If your plan does not cover Klayesta, using a pharmacy discount card can provide an alternative way to save on the prescription.

Medicaid coverage for Klayesta differs by state. Many state Medicaid formularies do not list brand-name Klayesta as a preferred drug, instead covering generic nystatin topical products. If Medicaid does not cover Klayesta, patients can explore pharmacy savings cards to help manage the cost.