Opdivo Prices at US Pharmacies

At the US pharmacies in our data, the lowest listed discount-card price for Opdivo is around $4,043.08. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.

Generic and brand-name pricing for Opdivo is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.

No, a generic equivalent is not currently available. Opdivo is the brand name for the biologic medication nivolumab.

Opdivo (nivolumab) is an injectable prescription medication used to treat several types of cancer, either alone or in combination with other therapies. It is a type of immunotherapy that helps the body's immune system recognize and attack cancer cells. It is administered by a healthcare professional as an intravenous infusion, typically over at least 30 minutes. Dosing frequency varies, from every two to four weeks, depending on whether it's used alone or with other drugs like Yervoy (ipilimumab) or chemotherapy. Approved uses include melanoma (including after surgery to prevent recurrence), non-small cell lung cancer, kidney cancer, Hodgkin lymphoma, head and neck cancer, bladder cancer, certain colorectal cancers, liver cancer (after prior treatment), esophageal cancer, stomach cancer, and malignant pleural mesothelioma. Due to its mechanism of action, it carries risks of serious immune-related side effects. Patients should discuss their full medical history and all medications with their doctor before starting treatment, and inform their doctor if they are pregnant, planning pregnancy, or breastfeeding.

Side effects vary depending on whether Opdivo is used alone or with other cancer drugs. Common side effects when used alone can include fatigue, nausea, vomiting, constipation, diarrhea, loss of appetite, muscle or back pain, cough, shortness of breath, skin rash or itching, headache, fever, and urinary tract infections. When combined with drugs like Yervoy or chemotherapy, the side effect profile may change based on the specific regimen. It is crucial to be aware of potential serious reactions requiring immediate medical attention. These include severe infusion reactions (symptoms like dizziness, trouble breathing, or itching during the infusion) and immune-mediated reactions that can affect the lungs (cough, chest pain), colon (severe diarrhea, abdominal pain), liver (jaundice, nausea), hormone-producing glands, skin, or kidneys (reduced urine output, swelling). Severe allergic reactions and life-threatening skin reactions are also possible. Patients should report any new or worsening symptoms to their healthcare team promptly.