Full price comparison · US & Canada
Opzelura (Opzelura) Rx Price Comparison: US vs Canada
Price comparison
See both prices
We don't have a directly comparable per-unit price for Opzelura yet — the full breakdown is below.
US · discount card
$1,903.02
per fill
Lowest listed pharmacy price
Canada
$13.22
per tablet
Lowest listed pharmacy price
US pharmacy prices — 60gm of 1.5%
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $1,903.02Lowest | $1,906.02 | $49.19 |
 Harris Teeter Pharmacy | $1,903.02Lowest | $1,906.02 | $49.19 |
 CVS Pharmacy | $1,997.72 | $2,000.72 | $49.19 |
 Walgreens | $2,007.30 | $2,010.30 | $49.19 |
 Publix | $2,021.36 | $2,024.36 | $49.19 |
 Costco | $2,069.63 | $2,072.63 | $49.19 |
 Food Lion | $2,186.72 | $2,186.72 | $49.19 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 CanadianPrescriptionDrugstore.com | $13.22 | — | $14.95 | $1,322.00Lowest |
 SPFPharmacy.com | $13.23 | — | $9.95 | $3,969.00 |
 InhalersOnline.com | $13.33 | — | $0.00 | $3,999.99 |
| SPFPharmacy.com | $13.55 | — | $9.95 | $1,354.50 |
| InhalersOnline.com | $13.60 | — | $0.00 | $1,359.99 |
| InhalersOnline.com | $14.33 | — | $0.00 | $4,299.99 |
| InhalersOnline.com | $14.60 | — | $0.00 | $1,459.99 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Opzelura.
Frequently asked questions
What's the cash price for Opzelura (Opzelura) in the US?
Our most recent US pharmacy data shows a low of roughly $1,903.02 for Opzelura with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
What do Canadian pharmacies charge for Opzelura (Opzelura)?
We found Canadian pricing for Opzelura starting near $13.22 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.
Why is Opzelura (Opzelura) priced differently in the US and Canada?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. Check the comparison table above for the specific numbers on Opzelura.
Does Opzelura have a generic equivalent?
Generic and brand-name pricing for Opzelura is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
How much will my insurance plan cover for Opzelura?
Many commercial insurance plans and government programs like Medicare may cover Opzelura. Your specific out-of-pocket cost will depend on your plan's formulary, deductible, and copay or coinsurance structure. It is advisable to contact your insurance provider or pharmacist for precise pricing information. In some cases, comparing your insurance copay against other available pharmacy savings options may be beneficial.
Is Opzelura covered by Medicare, and what would I pay?
Coverage for Opzelura under Medicare depends on the individual's Part D or Medicare Advantage plan details. Costs can vary widely based on the plan's coverage phase and pharmacy network. Patients are encouraged to check with their plan and compare the final price at their local pharmacy, as alternative savings methods may sometimes offer a lower out-of-pocket cost than the standard Medicare copay.
Is a generic form of Opzelura available?
No, a generic version of Opzelura (ruxolitinib cream) is not currently available in the United States. The brand-name drug is under patent protection, which is expected to last until around 2027. After that time, generic alternatives may become available. For now, patients should discuss all treatment and cost options with their healthcare provider.