US pharmacy pricing
Palynziq Prices at US Pharmacies
Lowest price found · US pharmacies
$20,950.76/fill
for Palynziq, across the pharmacies in our data
US pharmacy prices — 1ml of 20mg/ml
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $20,950.76Lowest | $20,953.76 | $29,279.00 |
 Harris Teeter Pharmacy | $20,950.76Lowest | $20,953.76 | $29,279.00 |
 Walgreens | $21,980.67 | $21,983.67 | $29,279.00 |
 Publix | $22,110.44 | $22,113.44 | $29,279.00 |
 Walmart Neighborhood Market | $22,493.51 | $22,496.51 | $29,279.00 |
 Walmart Pharmacy | $22,493.51 | $22,496.51 | $29,279.00 |
 Costco | $22,621.52 | $22,624.52 | $29,279.00 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Palynziq.
Frequently asked questions
What's the cash price for Palynziq (Palynziq) in the US?
Our most recent US pharmacy data shows a low of roughly $20,950.76 for Palynziq with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
Does Palynziq have a generic equivalent?
Generic and brand-name pricing for Palynziq is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
How much will I pay for Palynziq with my insurance plan?
The cost of Palynziq with insurance depends entirely on the specifics of your plan, including whether the drug is covered on your formulary, your deductible, and your coinsurance or copay. Coverage for this medication is not guaranteed and varies between insurers and plans. You should contact your insurance provider directly to confirm coverage details and your expected out-of-pocket cost. For patients with Medicare or Medicaid, coverage rules also apply. If your insurance provides only partial coverage or denies the claim, you can inquire about other potential savings options, such as pharmacy discount programs or manufacturer patient assistance, to help manage the remaining cost.
Is there a generic version of Palynziq?
Palynziq is a brand-name biologic drug produced by BioMarin Pharmaceuticals. As of now, no generic (biosimilar) equivalent of Palynziq has been approved for sale in the United States.