Full price comparison · US & Canada
Astagraf Xl (Tacrolimus Er) Rx Price Comparison: US vs Canada — Save Up to 77% in the US
Cheaper in the US
0%
lower price for Tacrolimus Er, based on the lowest comparable per-unit prices we found
US · discount card
$618.80
per fill
Lowest listed pharmacy price
US · Cost Plus Drugs
$0.073
per unit
Published price, no card needed
Canada
$0.320
per tablet
Lowest listed pharmacy price
US pharmacy prices — 1mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
| $618.80Lowest | $621.80 | $844.99 | |
| $654.95 | $657.95 | $844.99 | |
| $1,008.65 | $1,011.65 | $844.99 | |
| $1,527.15 | $1,530.15 | $844.99 | |
| $1,527.15 | $1,530.15 | $844.99 | |
| $1,632.00 | $1,635.00 | $844.99 | |
| $1,632.00 | $1,635.00 | $844.99 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
Initial · Defaultfrom $80.23
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $2.67 | — | $0.00 | $80.23Lowest | |
| $2.97 | — | $0.00 | $89.14 |
Generic · 0.0003from $21.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| RxOutreach.org | $0.350 | — | $0.00 | $21.00Lowest |
| $0.750 | — | $0.00 | $134.85 | |
| $0.790 | — | Free | $158.72 | |
| $0.830 | — | $0.00 | $149.83 | |
| $0.850 | — | Free | $169.99 | |
| $0.900 | — | Free | $90.09 | |
| $1.00 | — | $14.95 | $600.00 | |
| $1.01 | — | Free | $100.99 | |
| $1.14 | — | $0.00 | $684.52 | |
| $1.27 | — | $0.00 | $760.58 | |
| $1.27 | — | $14.95 | $763.33 | |
| $1.36 | — | $0.00 | $162.84 | |
| $1.44 | — | $14.95 | $143.75 | |
| $1.61 | — | $0.00 | $160.58 | |
| $1.78 | — | $0.00 | $178.42 | |
| $1.83 | — | $14.95 | $183.04 | |
| $1.84 | — | $0.00 | $55.22 | |
| $1.90 | — | $0.00 | $190.04 | |
| $2.05 | — | $0.00 | $61.36 | |
| $2.53 | — | $9.95 | $253.47 | |
| $4.20 | — | $9.95 | $126.00 | |
| $4.23 | — | $0.00 | $42.31 | |
| $4.50 | — | $0.00 | $134.99 |
Generic · 0.001from $21.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| RxOutreach.org | $0.350 | — | $0.00 | $21.00Lowest |
| $0.750 | — | $0.00 | $134.85 | |
| $0.790 | — | Free | $158.72 | |
| $0.830 | — | $0.00 | $149.83 | |
| $0.850 | — | Free | $169.99 | |
| $0.900 | — | Free | $90.09 | |
| $1.00 | — | $14.95 | $600.00 | |
| $1.01 | — | Free | $100.99 | |
| $1.14 | — | $0.00 | $684.52 | |
| $1.27 | — | $0.00 | $760.58 | |
| $1.27 | — | $14.95 | $763.33 | |
| $1.36 | — | $0.00 | $162.84 | |
| $1.44 | — | $14.95 | $143.75 | |
| $1.61 | — | $0.00 | $160.58 | |
| $1.78 | — | $0.00 | $178.42 | |
| $1.83 | — | $14.95 | $183.04 | |
| $1.84 | — | $0.00 | $55.22 | |
| $1.90 | — | $0.00 | $190.04 | |
| $2.05 | — | $0.00 | $61.36 | |
| $2.53 | — | $9.95 | $253.47 | |
| $4.20 | — | $9.95 | $126.00 | |
| $4.23 | — | $0.00 | $42.31 | |
| $4.50 | — | $0.00 | $134.99 |
Generic · 0.03 %from $27.53
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $27.53 | — | $14.95 | $27.53Lowest | |
| $27.53 | — | $14.95 | $82.58 |
Generic · 0.1 %from $27.43
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.950 | — | $14.95 | $57.25Lowest | |
| $0.960 | — | Free | $96.21 | |
| $1.07 | — | Free | $106.99 | |
| $1.21 | — | $14.95 | $60.25 | |
| $1.33 | — | $14.95 | $39.77 | |
| $1.37 | — | Free | $27.43 | |
| $1.80 | — | $0.00 | $108.06 | |
| $1.90 | — | Free | $37.99 | |
| $2.15 | — | $14.95 | $128.86 | |
| $2.27 | — | $14.95 | $68.22 | |
| $2.64 | — | $0.00 | $52.76 |
Generic · 0.1 %/10 %from $56.62
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $15.73 | — | $14.95 | $78.64Lowest | |
| $18.87 | — | $14.95 | $56.62 |
Generic · 0.25 mgfrom $27.23
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.320 | — | $0.00 | $57.83Lowest | |
| $0.360 | — | $0.00 | $64.26 | |
| $0.910 | — | $0.00 | $27.23 | |
| $1.01 | — | $0.00 | $30.26 |
Generic · 0.5 mgfrom $21.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| RxOutreach.org | $0.350 | — | $0.00 | $21.00Lowest |
| $0.720 | — | $0.00 | $86.05 | |
| $0.800 | — | $0.00 | $95.61 | |
| $0.850 | 90 | $14.95 | $76.55 | |
| $0.940 | 60 | $14.95 | $56.14 | |
| $0.970 | — | $0.00 | $116.60 | |
| $1.16 | — | $0.00 | $69.61 | |
| $1.25 | — | $0.00 | $37.44 | |
| $1.39 | — | $0.00 | $41.60 | |
| $1.42 | — | $0.00 | $142.15 | |
| $1.49 | — | Free | $148.66 | |
| $1.60 | — | Free | $159.99 | |
| $2.12 | — | $9.95 | $211.58 |
Generic · 2 mgfrom $94.44
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $1.35 | — | $0.00 | $242.54Lowest | |
| $1.50 | — | $0.00 | $269.49 | |
| $3.15 | — | $0.00 | $94.44 | |
| $3.50 | — | $0.00 | $104.93 |
Generic · 3 mgfrom $288.75
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $8.78 | — | $0.00 | $789.99Lowest | |
| $8.93 | — | $9.95 | $803.25 | |
| $9.63 | — | $9.95 | $288.75 | |
| $9.67 | — | $0.00 | $289.99 |
Generic · 5 mgfrom $55.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| RxOutreach.org | $0.920 | — | $0.00 | $55.00Lowest |
| $4.46 | — | Free | $222.78 | |
| $4.50 | — | $0.00 | $450.02 | |
| $4.68 | — | Free | $233.99 | |
| $5.83 | 90 | $14.95 | $524.67 | |
| $6.41 | 60 | $14.95 | $384.76 | |
| $10.40 | 100 | $0.00 | $1,039.99 | |
| $11.49 | 100 | $9.95 | $1,148.70 | |
| $14.83 | — | $0.00 | $444.99 | |
| $15.05 | — | $9.95 | $451.50 |
Brand · 0.0003from $21.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| RxOutreach.org | $0.350 | — | $0.00 | $21.00Lowest |
| $0.750 | — | $0.00 | $134.85 | |
| $0.790 | — | Free | $158.72 | |
| $0.830 | — | $0.00 | $149.83 | |
| $0.850 | — | Free | $169.99 | |
| $0.900 | — | Free | $90.09 | |
| $1.00 | — | $14.95 | $600.00 | |
| $1.01 | — | Free | $100.99 | |
| $1.14 | — | $0.00 | $684.52 | |
| $1.27 | — | $0.00 | $760.58 | |
| $1.27 | — | $14.95 | $763.33 | |
| $1.36 | — | $0.00 | $162.84 | |
| $1.44 | — | $14.95 | $143.75 | |
| $1.61 | — | $0.00 | $160.58 | |
| $1.78 | — | $0.00 | $178.42 | |
| $1.83 | — | $14.95 | $183.04 | |
| $1.84 | — | $0.00 | $55.22 | |
| $1.90 | — | $0.00 | $190.04 | |
| $2.05 | — | $0.00 | $61.36 | |
| $2.53 | — | $9.95 | $253.47 | |
| $4.20 | — | $9.95 | $126.00 | |
| $4.23 | — | $0.00 | $42.31 | |
| $4.50 | — | $0.00 | $134.99 |
Brand · 0.001from $21.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| RxOutreach.org | $0.350 | — | $0.00 | $21.00Lowest |
| $0.750 | — | $0.00 | $134.85 | |
| $0.790 | — | Free | $158.72 | |
| $0.830 | — | $0.00 | $149.83 | |
| $0.850 | — | Free | $169.99 | |
| $0.900 | — | Free | $90.09 | |
| $1.00 | — | $14.95 | $600.00 | |
| $1.01 | — | Free | $100.99 | |
| $1.14 | — | $0.00 | $684.52 | |
| $1.27 | — | $0.00 | $760.58 | |
| $1.27 | — | $14.95 | $763.33 | |
| $1.36 | — | $0.00 | $162.84 | |
| $1.44 | — | $14.95 | $143.75 | |
| $1.61 | — | $0.00 | $160.58 | |
| $1.78 | — | $0.00 | $178.42 | |
| $1.83 | — | $14.95 | $183.04 | |
| $1.84 | — | $0.00 | $55.22 | |
| $1.90 | — | $0.00 | $190.04 | |
| $2.05 | — | $0.00 | $61.36 | |
| $2.53 | — | $9.95 | $253.47 | |
| $4.20 | — | $9.95 | $126.00 | |
| $4.23 | — | $0.00 | $42.31 | |
| $4.50 | — | $0.00 | $134.99 |
Brand · 0.03 %from $27.53
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $27.53 | — | $14.95 | $27.53Lowest | |
| $27.53 | — | $14.95 | $82.58 |
Brand · 0.1 %from $27.43
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.950 | — | $14.95 | $57.25Lowest | |
| $0.960 | — | Free | $96.21 | |
| $1.07 | — | Free | $106.99 | |
| $1.21 | — | $14.95 | $60.25 | |
| $1.33 | — | $14.95 | $39.77 | |
| $1.37 | — | Free | $27.43 | |
| $1.80 | — | $0.00 | $108.06 | |
| $1.90 | — | Free | $37.99 | |
| $2.15 | — | $14.95 | $128.86 | |
| $2.27 | — | $14.95 | $68.22 | |
| $2.64 | — | $0.00 | $52.76 |
Brand · 0.1 %/10 %from $56.62
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $15.73 | — | $14.95 | $78.64Lowest | |
| $18.87 | — | $14.95 | $56.62 |
Brand · 0.25 mgfrom $27.23
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $0.320 | — | $0.00 | $57.83Lowest | |
| $0.360 | — | $0.00 | $64.26 | |
| $0.910 | — | $0.00 | $27.23 | |
| $1.01 | — | $0.00 | $30.26 |
Brand · 0.5 mgfrom $21.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| RxOutreach.org | $0.350 | — | $0.00 | $21.00Lowest |
| $0.720 | — | $0.00 | $86.05 | |
| $0.800 | — | $0.00 | $95.61 | |
| $0.850 | 90 | $14.95 | $76.55 | |
| $0.940 | 60 | $14.95 | $56.14 | |
| $0.970 | — | $0.00 | $116.60 | |
| $1.16 | — | $0.00 | $69.61 | |
| $1.25 | — | $0.00 | $37.44 | |
| $1.39 | — | $0.00 | $41.60 | |
| $1.42 | — | $0.00 | $142.15 | |
| $1.49 | — | Free | $148.66 | |
| $1.60 | — | Free | $159.99 | |
| $2.12 | — | $9.95 | $211.58 |
Brand · 2 mgfrom $94.44
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $1.35 | — | $0.00 | $242.54Lowest | |
| $1.50 | — | $0.00 | $269.49 | |
| $3.15 | — | $0.00 | $94.44 | |
| $3.50 | — | $0.00 | $104.93 |
Brand · 3 mgfrom $288.75
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| $8.78 | — | $0.00 | $789.99Lowest | |
| $8.93 | — | $9.95 | $803.25 | |
| $9.63 | — | $9.95 | $288.75 | |
| $9.67 | — | $0.00 | $289.99 |
Brand · 5 mgfrom $55.00
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| RxOutreach.org | $0.920 | — | $0.00 | $55.00Lowest |
| $4.46 | — | Free | $222.78 | |
| $4.50 | — | $0.00 | $450.02 | |
| $4.68 | — | Free | $233.99 | |
| $5.83 | 90 | $14.95 | $524.67 | |
| $6.41 | 60 | $14.95 | $384.76 | |
| $10.40 | 100 | $0.00 | $1,039.99 | |
| $11.49 | 100 | $9.95 | $1,148.70 | |
| $14.83 | — | $0.00 | $444.99 | |
| $15.05 | — | $9.95 | $451.50 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Tacrolimus Er.
Frequently asked questions
How much does Tacrolimus Er (Astagraf Xl) cost without insurance?
Our most recent US pharmacy data shows a low of roughly $618.80 for Tacrolimus Er with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
Is Tacrolimus Er (Astagraf Xl) available through Cost Plus Drugs?
Yes — Cost Plus Drugs lists Tacrolimus Er at roughly $0.073 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
What do Canadian pharmacies charge for Tacrolimus Er (Astagraf Xl)?
We found Canadian pricing for Tacrolimus Er starting near $0.320 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.
Why is Tacrolimus Er (Astagraf Xl) priced differently in the US and Canada?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.
What is the typical cost of Astagraf XL without insurance coverage?
The cash price for Astagraf XL at most retail pharmacies can be substantial. For a supply of 60 capsules (5mg, extended-release), the retail price is often quoted at a high figure. Patients without insurance can explore pharmacy savings programs or discount cards, which may offer a significantly lower price at participating pharmacies.
How much will Astagraf XL cost with my insurance plan?
Your out-of-pocket cost for Astagraf XL with insurance depends entirely on the specifics of your plan, including your deductible, copay, or coinsurance. It can be helpful to compare your insurance copay against the price available through pharmacy discount programs, as the latter may sometimes offer a lower final cost.
Is Astagraf XL covered by Medicare, and what are the potential costs?
Astagraf XL is often considered a necessary part of post-transplant care. While it may not typically be covered under a standard Medicare Part D prescription drug plan, it can be covered as a medical benefit under Medicare Part B following a transplant surgery. If Part B does not apply, coverage may fall under Part D. Costs vary based on your Medicare plan details and coverage phase. For those without Medicare coverage, investigating other savings options can help manage the prescription's expense.