US pharmacy pricing
Rebif Cost Without Insurance — US Pharmacy Price Guide
Lowest price found · US pharmacies
$10,738.75/fill
for Rebif, across the pharmacies in our data
US pharmacy prices — 0.5ml of 44mcg/0.5ml
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $10,738.75Lowest | $10,741.75 | $824.12 |
 Harris Teeter Pharmacy | $10,738.75Lowest | $10,741.75 | $824.12 |
 Walgreens | $11,289.03 | $11,292.03 | $824.12 |
 Publix | $11,361.85 | $11,361.85 | $824.12 |
 Costco | $11,630.12 | $11,633.12 | $824.12 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Rebif.
Frequently asked questions
What's the cash price for Rebif (Rebif) in the US?
Our most recent US pharmacy data shows a low of roughly $10,738.75 for Rebif with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
Does Rebif have a generic equivalent?
Generic and brand-name pricing for Rebif is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
How does insurance affect the cost of Rebif?
The out-of-pocket cost for Rebif with insurance depends entirely on your specific plan's formulary, deductible, and copay structure. Copays can sometimes be quite high. In many cases, the price obtained through a pharmacy discount program or manufacturer coupon may be lower than your insurance copay. It is advisable to ask your pharmacist to compare the price using your insurance benefits against the price available through a non-insurance savings option, as this comparison can lead to substantial savings.
Is Rebif covered by Medicare, and what are the costs?
Coverage for Rebif under Medicare Part D or Medicare Advantage prescription drug plans is not guaranteed and varies by plan. Some Medicare plans may offer partial coverage. If your plan does not cover the medication or requires a high copay, exploring alternative savings methods, such as manufacturer patient assistance programs or pharmacy discount cards, can be beneficial. These options can provide access to the medication at a reduced price.
Is a generic version of Rebif available?
No, Rebif is currently only available as a brand-name medication. A bioequivalent generic version of interferon beta-1a (the active ingredient in Rebif) is not on the market at this time.