US pharmacy pricing

Safyral Prices at US Pharmacies

Brand availableRx requiredUS pricing onlydisp pack

Lowest price found · US pharmacies

$60.67/fill

for Drospiren-Eth Estrad-Levomefol, across the pharmacies in our data

Discount card

$60.67

per fill

Lowest listed pharmacy price

Lowest

Cost Plus Drugs

$36.99

per unit

Published price, no card needed

US pharmacy prices — 1 package (28 tablets), 3-0.03-0.451mg

PharmacyDiscount-card priceRegular cash priceAverage retail
CVS Pharmacy$60.67Lowest$63.67$163.95
Walgreens$100.16$103.16$163.95
Publix$102.70$105.70$163.95
Kroger Pharmacy$116.98$119.98$89.58
Harris Teeter Pharmacy$116.98$119.98$89.58
Food Lion$120.00$120.00$107.02
Costco$122.06$122.06$107.02
Walmart Neighborhood Market$152.90$155.90$163.95
Walmart Pharmacy$152.90$155.90$163.95

"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.

Interchangeable forms

Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Drospiren-Eth Estrad-Levomefol.

Generic clinical forms
levomefolate calcium 0.451 MG Oral Tablet

Frequently asked questions

Is Drospiren-Eth Estrad-Levomefol (Safyral) expensive if I don't have insurance?

Our most recent US pharmacy data shows a low of roughly $60.67 for Drospiren-Eth Estrad-Levomefol with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Is Drospiren-Eth Estrad-Levomefol (Safyral) available through Cost Plus Drugs?

Yes — Cost Plus Drugs lists Drospiren-Eth Estrad-Levomefol at roughly $36.99 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

Does Drospiren-Eth Estrad-Levomefol have a generic equivalent?

Generic and brand-name pricing for Drospiren-Eth Estrad-Levomefol is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.

What will Safyral cost if I have health insurance?

The out-of-pocket cost for Safyral with insurance varies significantly depending on your specific plan's formulary, deductible, and copay structure. To determine your exact cost, contact your insurance provider. Regardless of insurance status, you may also inquire with your pharmacy about additional savings programs or discount cards that could further reduce your expense for this medication.

Is Safyral typically covered by Medicare, and what is the cost?

Safyral is not commonly covered under standard Medicare Part D plans. Patients who need this medication and are paying out-of-pocket should explore all available savings options. Pharmacy discount programs and manufacturer coupons may offer substantial price reductions, making the medication more affordable for those without coverage.

Is a generic version of Safyral available?

Yes. Tydemy is the generic form of the brand-name oral contraceptive Safyral, which is manufactured by Bayer HealthCare Pharmaceuticals.