US pharmacy pricing

Where to Find the Cheapest Sephience Price

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Lowest price found · US pharmacies

$8,017.02/fill

for Sephience, across the pharmacies in our data

US pharmacy prices — 250mg

PharmacyDiscount-card priceRegular cash priceAverage retail
Kroger Pharmacy$8,017.02Lowest$8,020.02$9,774.44
Harris Teeter Pharmacy$8,017.02Lowest$8,020.02$9,774.44
Walgreens$8,412.14$8,415.14$9,774.44
Publix$8,462.57$8,465.57$9,774.44
Walmart Neighborhood Market$8,607.59$8,610.59$9,774.44
Walmart Pharmacy$8,607.59$8,610.59$9,774.44
Costco$8,656.25$8,659.25$9,774.44

"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.

Interchangeable forms

Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Sephience.

Generic clinical forms
sepiapterin 1000 MG Oral Powder

Frequently asked questions

How much does Sephience (Sephience) cost without insurance?

Our most recent US pharmacy data shows a low of roughly $8,017.02 for Sephience with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Does Sephience have a generic equivalent?

Generic and brand-name pricing for Sephience is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.

How much does Sephience cost with insurance?

The cost of Sephience with insurance varies significantly depending on your specific plan's formulary, coverage rules, and your deductible or coinsurance requirements. It's essential to contact your insurance provider directly to understand if Sephience is covered and what your expected copay would be. If your plan does not cover the medication, or if you have Medicare or Medicaid with coverage gaps, you may be able to find lower prices by comparing cash prices and using available pharmacy savings programs or manufacturer coupons. Checking these options can sometimes provide a more affordable rate than your insurance copay.

Is generic Sephience available?

No, a generic version of Sephience is not currently available. Sephience is a brand-name medication developed by PTC Therapeutics.