US pharmacy pricing

Sernivo Cost Without Insurance — US Pharmacy Price Guide

Brand availableRx requiredUS pricing onlybottle

Lowest price found · US pharmacies

$1,224.50/fill

for Sernivo, across the pharmacies in our data

US pharmacy prices — 120ml of 0.05%

PharmacyDiscount-card priceRegular cash priceAverage retail
Kroger Pharmacy$1,224.50Lowest$1,227.50$16.19
Harris Teeter Pharmacy$1,224.50Lowest$1,227.50$16.19
Food Lion$1,283.00$1,283.00$16.19
Walgreens$1,286.25$1,289.25$16.19
CVS Pharmacy$1,287.93$1,290.93$16.19
Publix$1,295.00$1,298.00$16.19
Walmart Neighborhood Market$1,315.01$1,318.01$16.19
Walmart Pharmacy$1,315.01$1,318.01$16.19
Costco$1,322.00$1,325.00$16.19

"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.

Interchangeable forms

Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Sernivo.

Generic clinical forms
betamethasone 0.5 MG/ML Topical Spray

Frequently asked questions

How much does Sernivo (Sernivo) cost without insurance?

Our most recent US pharmacy data shows a low of roughly $1,224.50 for Sernivo with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Does Sernivo have a generic equivalent?

Generic and brand-name pricing for Sernivo is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.

Is a generic version of Sernivo available?

No, a generic equivalent for Sernivo (betamethasone dipropionate spray, 0.05%) is not currently on the market. It remains available only as a brand-name product manufactured by Encore Dermatology Inc.

What is Sernivo, and what is it used for?

Sernivo is a prescription topical corticosteroid containing the active ingredient betamethasone dipropionate. It is used to reduce inflammation, itching, redness, and swelling associated with several dermatological conditions, most commonly eczema and plaque psoriasis. It works by inhibiting the release of substances in the body that cause inflammation. Before use, inform your doctor about all medications you take and any skin thinning at the application site. Do not use Sernivo if you are allergic to any of its ingredients. Its safety during pregnancy or breastfeeding is not established, so discuss this with your healthcare provider. This medication is not approved for use in children under 18 and should be applied exactly as directed by your physician.

What are the potential side effects of Sernivo?

Common side effects of Sernivo are typically localized to the application site and may include itching, burning, stinging, pain, and thinning of the skin (atrophy). If your skin condition worsens during treatment, discontinue use and contact your doctor promptly. This is not an exhaustive list of side effects, and others may occur. You can report any adverse reactions directly to the U.S. Food and Drug Administration (FDA).