US pharmacy pricing
Seysara Prices at US Pharmacies
Lowest price found · US pharmacies
$1,095.66/fill
for Seysara, across the pharmacies in our data
US pharmacy prices — 100mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $1,095.66Lowest | $1,098.66 | $43.49 |
 Harris Teeter Pharmacy | $1,095.66Lowest | $1,098.66 | $43.49 |
 Food Lion | $1,148.62 | $1,148.62 | $43.49 |
 Walgreens | $1,151.08 | $1,154.08 | $43.49 |
 CVS Pharmacy | $1,154.43 | $1,157.43 | $43.49 |
 Publix | $1,159.04 | $1,162.04 | $43.49 |
 Walmart Neighborhood Market | $1,176.68 | $1,179.68 | $43.49 |
 Walmart Pharmacy | $1,176.68 | $1,179.68 | $43.49 |
 Costco | $1,182.88 | $1,185.88 | $43.49 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Seysara.
Frequently asked questions
What's the cash price for Seysara (Seysara) in the US?
Our most recent US pharmacy data shows a low of roughly $1,095.66 for Seysara with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
Does Seysara have a generic equivalent?
Generic and brand-name pricing for Seysara is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
Is a lower-cost generic version of Seysara available?
No, Seysara is only available as a brand-name medication. Its active ingredient is sarecycline, but no FDA-approved generic alternatives exist in the U.S. market at this time. For patients seeking other tetracycline-class treatment options for acne, a different branded medication like Oracea (doxycycline) may be considered, though it is not a direct generic substitute and requires a separate prescription.
What is Seysara, and how is it used?
Seysara is a prescription antibiotic in the tetracycline class, specifically approved to treat moderate to severe inflammatory acne. It is an oral tablet taken once daily, suitable for patients aged nine years and older. Important safety information includes: it is not effective against viral infections like colds or flu; it should be avoided by those allergic to tetracycline antibiotics; it can increase sun sensitivity, necessitating sun protection; adequate fluid intake is recommended to reduce esophageal irritation; and it is not advised during pregnancy or breastfeeding due to risks of impaired bone development and permanent tooth discoloration in the infant. Always take the medication exactly as prescribed by your healthcare provider and discuss your full medical history and current medications with them before starting treatment.
What side effects are associated with Seysara?
Nausea is the most frequently reported side effect of Seysara. As with any medication, other adverse reactions are possible. For a complete list of potential side effects and guidance on managing them, consult your prescribing doctor or pharmacist. Patients and caregivers can also report any suspected side effects directly to the U.S. Food and Drug Administration (FDA).