Simponi Prices at US Pharmacies

At the US pharmacies in our data, the lowest listed discount-card price for Simponi is around $6,518.94. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.

Generic and brand-name pricing for Simponi is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.

Simponi is a brand-name tumor necrosis factor (TNF) inhibitor manufactured by Janssen Biotech, Inc. A generic version of this biologic medication is not currently on the market. Simponi Aria is a related intravenous formulation also produced by the same manufacturer.

Simponi is a prescription medication classified as a TNF blocker. It is approved to treat symptoms of several inflammatory arthritic conditions: rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. It is also used to manage moderate to severe ulcerative colitis. The drug works by targeting and inhibiting tumor necrosis factor (TNF), a protein in the body that drives inflammation, joint damage, and swelling. By reducing this inflammation, it can help preserve joint function. For certain forms of arthritis, it may be prescribed alone or alongside another medication like methotrexate. For ulcerative colitis, treatment aims to alleviate symptoms such as abdominal pain, cramping, diarrhea, and rectal bleeding. Simponi is administered either as a subcutaneous injection (under the skin) or as an intravenous infusion. It is not approved for use in individuals under 18 years of age. Do not use Simponi if you have a known allergy to golimumab or any other ingredient in the formulation. Before starting treatment, a thorough discussion with your doctor is essential. You must disclose your full medical history, including any past or present conditions like Hepatitis B, diabetes, cancer (especially skin cancer or lymphoma), HIV, psoriasis, a weakened immune system, or latex allergy. Report any known exposure to tuberculosis or serious fungal infections. Inform your healthcare provider about all medications and supplements you take, including prescription drugs, over-the-counter products, vitamins, and herbal remedies. Specific mention of drugs like anakinra, tocilizumab, rituximab, or abatacept is important. Also, discuss any plans for live vaccinations. Always use Simponi exactly as prescribed. Your doctor will determine the appropriate formulation (injection or infusion) and dosing schedule based on your condition. While intravenous doses are administered by a healthcare professional, many patients can learn to self-administer the subcutaneous injection after proper training.

Common side effects include upper respiratory infections, reactions at the injection site, and viral infections. A notable, less common effect is the new onset or worsening of psoriasis, which requires prompt medical attention if red, scaly patches or pus-filled bumps appear. Because Simponi suppresses part of the immune system, it can lower your body's ability to fight infections. Serious, widespread infections caused by bacteria, viruses, or fungi have been reported, particularly in patients aged 65 and older. Seek immediate medical care if you develop signs of infection such as fever, chills, sweats, cough, shortness of breath, diarrhea, weight loss, or skin sores. TNF blockers like Simponi may increase the risk of heart failure; your doctor will monitor you closely if you have this condition. Report new or worsening symptoms like shortness of breath, chest discomfort, swelling in the ankles or feet, or sudden weight gain. There is an increased risk of developing certain cancers, including lymphoma (especially in teenage and young adult males with ulcerative colitis) and skin cancers. Your healthcare provider may recommend regular skin exams and, for women, cervical cancer screening. Liver problems are possible; alert your doctor to symptoms like persistent right-sided abdominal pain, loss of appetite, dark urine, easy bruising, or yellowing of the skin or eyes (jaundice). Rare nervous system disorders, such as multiple sclerosis or Guillain-Barré syndrome, have been associated with its use. Report any vision changes, weakness in limbs, or numbness and tingling. Severe allergic reactions, though uncommon, require emergency treatment. Signs may include hives, rash, difficulty breathing, or swelling of the face, lips, throat, or tongue. This list does not cover all possible side effects. Discuss the complete risk profile with your prescribing physician. You can also report adverse effects directly to the FDA's MedWatch program.