Sirolimus Prices — US Pharmacy Cost vs Canada — Save Up to 31% in the US

At the US pharmacies in our data, the lowest listed discount-card price for Sirolimus is around $34.96. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.

Yes — Cost Plus Drugs lists Sirolimus at roughly $0.500 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

Canadian pharmacy listings in our data show Sirolimus priced from about $0.720 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.

Sirolimus is the generic name for the medication. It is manufactured by several companies, including Zydus, Amneal, and Teva. The original brand name version is called Rapamune.

Sirolimus is a generic prescription immunosuppressant used to prevent organ rejection following a kidney transplant. It is part of a multi-drug regimen, typically taken alongside cyclosporine and a corticosteroid. The medication works by blocking specific chemicals in the body that activate white blood cells, thereby 'slowing down' the immune system's attack on the transplanted organ. Treatment begins shortly after surgery. Sirolimus carries a boxed warning from the FDA due to serious risks, including an increased susceptibility to infections and a higher potential for developing lymphoma and other cancers. It should only be prescribed by a physician experienced in immunosuppressive therapy for kidney transplant patients and is not approved for use in lung or liver transplant recipients. Always discuss potential side effects and your full medical history, including all medications and supplements you take, with your doctor or healthcare provider.