US pharmacy pricing
Skyrizi Prices at US Pharmacies
Lowest price found · US pharmacies
$10,360.32/fill
for Skyrizi, across the pharmacies in our data
US pharmacy prices — 10ml of 600mg/10ml
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $10,360.32Lowest | $10,363.32 | $6,435.00 |
 Harris Teeter Pharmacy | $10,360.32Lowest | $10,363.32 | $6,435.00 |
 Walgreens | $10,898.24 | $10,901.24 | $6,435.00 |
 Publix | $10,966.52 | $10,969.52 | $6,435.00 |
 Costco | $11,231.60 | $11,234.60 | $6,435.00 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Skyrizi.
Frequently asked questions
What's the cash price for Skyrizi (Skyrizi) in the US?
At the US pharmacies in our data, the lowest listed discount-card price for Skyrizi is around $10,360.32. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Is a generic version of Skyrizi available?
Generic and brand-name pricing for Skyrizi is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
How does insurance affect the cost of Skyrizi?
If you have insurance, your plan will likely cover a portion of Skyrizi's cost, but you will still be responsible for a copay or coinsurance amount. The final out-of-pocket expense depends entirely on your specific plan's formulary, coverage tier, and deductible status. It is advisable to contact your insurance provider for details on your expected cost and to compare that amount with prices available through other prescription savings options to ensure you are getting the best possible price.
Is a generic version of Skyrizi available?
No, a generic (biosimilar) version of Skyrizi is not currently available. Skyrizi is a biologic medication protected by patent, so only the brand-name product containing risankizumab-rzaa is on the market at this time.
What is Skyrizi and what conditions does it treat?
Skyrizi is a prescription biologic medication approved to treat moderate to severe plaque psoriasis, active psoriatic arthritis, and Crohn's disease. These are chronic inflammatory conditions driven by an overactive immune system. Its active ingredient, risankizumab-rzaa, is a monoclonal antibody designed to bind specifically to interleukin-23 (IL-23), a cytokine that promotes inflammation. By blocking this protein, Skyrizi can help reduce the inflammatory response and alleviate symptoms.