Full price comparison · US & Canada
Bactrim (Sulfamethoxazole-Trimethoprim) Rx Price Comparison: US vs Canada — Save Up to 89% in the US
Cheaper in the US
0%
lower price for Sulfamethoxazole-Trimethoprim, based on the lowest comparable per-unit prices we found
US · discount card
$2.80
per fill
Lowest listed pharmacy price
US · Cost Plus Drugs
$0.029
per unit
Published price, no card needed
Canada
$0.270
per tablet
Lowest listed pharmacy price
US pharmacy prices — 800-160mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $2.80Lowest | $5.80 | $48.83 |
 Harris Teeter Pharmacy | $2.80Lowest | $5.80 | $48.83 |
 Walmart Neighborhood Market | $4.83 | $7.83 | $48.83 |
 Walmart Pharmacy | $4.83 | $7.83 | $48.83 |
 Walgreens | $8.85 | $11.85 | $48.83 |
 Food Lion | $9.43 | $9.43 | $48.83 |
 CVS Pharmacy | $11.84 | $14.84 | $48.83 |
 Costco | $11.99 | $11.99 | $48.83 |
 Publix | $13.65 | $16.65 | $48.83 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
Initial · 200 mg/5 mL/40 mg/5 mLfrom $96.21
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 CanadianPharmacyAdvantage.com | $0.960 | — | Free | $96.21Lowest |
 CanadaPharmacies.com | $1.07 | — | Free | $106.99 |
Initial · 800 mg/160 mgfrom $19.73
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 LifeRxPharmacy.com | $0.270 | 90 | $14.95 | $24.67Lowest |
| CanadianPharmacyAdvantage.com | $0.300 | 100 | Free | $30.27 |
| LifeRxPharmacy.com | $0.330 | 60 | $14.95 | $19.73 |
| CanadaPharmacies.com | $0.410 | 100 | Free | $40.99 |
 SPFPharmacy.com | $0.800 | 100 | $9.95 | $80.00 |
 InhalersOnline.com | $0.950 | 100 | $0.00 | $94.99 |
 CanadianPrescriptionDrugstore.com | $0.970 | 180 | $14.95 | $175.00 |
 CanadaPharmacyPro.com | $7.66 | 10 | $14.95 | $76.59 |
Generic · 800 mg/160 mgfrom $64.75
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| InhalersOnline.com | $2.08 | 100 | $0.00 | $208.30Lowest |
| InhalersOnline.com | $6.48 | 10 | $0.00 | $64.75 |
Brand · 800 mg/160 mgfrom $64.75
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| InhalersOnline.com | $2.08 | 100 | $0.00 | $208.30Lowest |
| InhalersOnline.com | $6.48 | 10 | $0.00 | $64.75 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Sulfamethoxazole-Trimethoprim.
Frequently asked questions
What's the cash price for Sulfamethoxazole-Trimethoprim (Bactrim) in the US?
Our most recent US pharmacy data shows a low of roughly $2.80 for Sulfamethoxazole-Trimethoprim with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
Is Sulfamethoxazole-Trimethoprim (Bactrim) available through Cost Plus Drugs?
Yes — Cost Plus Drugs lists Sulfamethoxazole-Trimethoprim at roughly $0.029 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
What do Canadian pharmacies charge for Sulfamethoxazole-Trimethoprim (Bactrim)?
We found Canadian pricing for Sulfamethoxazole-Trimethoprim starting near $0.270 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.
Why is Sulfamethoxazole-Trimethoprim (Bactrim) priced differently in the US and Canada?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.
Is Bactrim DS covered by Medicare, and what is the patient cost?
Medicare plans typically provide coverage for generic sulfamethoxazole-trimethoprim. The exact cost to you, including any copay or deductible, depends on your specific Medicare plan details. Contact your Medicare provider or pharmacist for precise pricing information.
Is a generic form of Bactrim DS available?
Yes. Bactrim DS is the brand name for the combination antibiotic containing sulfamethoxazole and trimethoprim. The generic version is sold under the name sulfamethoxazole-trimethoprim.
What is Bactrim DS and how is it used?
Bactrim DS is a combination antibiotic containing sulfamethoxazole and trimethoprim. It is FDA-approved to treat a range of bacterial infections such as ear infections, urinary tract infections, traveler's diarrhea, and pneumocystis pneumonia. The medication works by inhibiting bacterial growth and is taken orally, with or without food. Taking it with food may help if stomach upset occurs. It's crucial to take the full prescribed course at consistent times each day, even if symptoms improve, to prevent antibiotic resistance and recurrence of infection. This medication is not for viral or fungal infections and is not recommended for infants under two months old.