Full price comparison · US & Canada
Synjardy (Synjardy Xr) Rx Price Comparison: US vs Canada
Price comparison
See both prices
We don't have a directly comparable per-unit price for Synjardy Xr yet — the full breakdown is below.
US · discount card
$243.66
per fill
Lowest listed pharmacy price
Canada
$0.670
per tablet
Lowest listed pharmacy price
US pharmacy prices — 12.5-1000mg er 24hr (xr)
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $243.66Lowest | $246.66 | $18.59 |
 Harris Teeter Pharmacy | $243.66Lowest | $246.66 | $18.59 |
 Walgreens | $283.69 | $286.69 | $18.59 |
 Publix | $287.04 | $290.04 | $18.59 |
 Walmart Neighborhood Market | $296.53 | $299.53 | $18.59 |
 Walmart Pharmacy | $296.53 | $299.53 | $18.59 |
 CVS Pharmacy | $296.79 | $299.79 | $18.59 |
 Food Lion | $365.00 | $365.00 | $18.59 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
Initial · 5 mg/850 mgfrom $105.94
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 GoldStarMeds.com | $1.50 | 168 | $0.00 | $252.70Lowest |
 CanadianPrescriptionDrugstore.com | $1.54 | 168 | $14.95 | $259.00 |
 1800RxOnline.com | $1.67 | 168 | $0.00 | $280.79 |
| GoldStarMeds.com | $1.89 | 56 | $0.00 | $105.94 |
 LifeRxPharmacy.com | $1.95 | 168 | $14.95 | $326.84 |
| LifeRxPharmacy.com | $2.05 | 112 | $14.95 | $230.00 |
| 1800RxOnline.com | $2.10 | 56 | $0.00 | $117.71 |
 OffShoreCheapMeds.com | $2.12 | 168 | $14.95 | $356.90 |
| $2.14 | 112 | $14.95 | $239.91 | |
| OffShoreCheapMeds.com | $2.24 | 112 | $14.95 | $251.15 |
 InhalersOnline.com | $2.27 | 168 | $0.00 | $380.73 |
 SPFPharmacy.com | $2.35 | 180 | $9.95 | $422.16 |
| InhalersOnline.com | $2.46 | 180 | $0.00 | $441.90 |
| InhalersOnline.com | $2.48 | 56 | $0.00 | $139.08 |
 CanadaPharmacyPro.com | $2.49 | 180 | $14.95 | $448.92 |
| SPFPharmacy.com | $2.61 | 60 | $9.95 | $156.45 |
| CanadaPharmacyPro.com | $2.63 | 120 | $14.95 | $315.91 |
| $2.73 | 60 | $14.95 | $163.86 | |
| InhalersOnline.com | $2.81 | 60 | $0.00 | $168.78 |
Initial · 5 mg/1000 mgfrom $55.39
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| LifeRxPharmacy.com | $0.830 | 180 | $14.95 | $149.54Lowest |
| GoldStarMeds.com | $0.880 | 180 | $0.00 | $157.53 |
| OffShoreCheapMeds.com | $0.880 | 180 | $14.95 | $158.00 |
| InhalersOnline.com | $0.890 | 180 | $0.00 | $159.99 |
| LifeRxPharmacy.com | $0.920 | 60 | $14.95 | $55.39 |
| 1800RxOnline.com | $0.970 | 180 | $0.00 | $175.03 |
| OffShoreCheapMeds.com | $0.980 | 60 | $14.95 | $58.52 |
 CanadianPharmacyAdvantage.com | $1.05 | 180 | Free | $189.13 |
| GoldStarMeds.com | $1.06 | 60 | $0.00 | $63.87 |
 CanadaPharmacies.com | $1.11 | 180 | Free | $199.99 |
| 1800RxOnline.com | $1.18 | 60 | $0.00 | $70.97 |
| InhalersOnline.com | $1.25 | 60 | $0.00 | $74.99 |
| CanadianPharmacyAdvantage.com | $1.29 | 60 | Free | $77.43 |
| CanadianPrescriptionDrugstore.com | $1.30 | 180 | $14.95 | $234.00 |
| CanadaPharmacies.com | $1.47 | 60 | Free | $87.99 |
| GoldStarMeds.com | $1.50 | 168 | $0.00 | $252.70 |
| 1800RxOnline.com | $1.67 | 168 | $0.00 | $280.79 |
| GoldStarMeds.com | $1.89 | 56 | $0.00 | $105.94 |
| InhalersOnline.com | $2.10 | 180 | $0.00 | $377.10 |
| 1800RxOnline.com | $2.10 | 56 | $0.00 | $117.71 |
| SPFPharmacy.com | $2.35 | 180 | $9.95 | $422.16 |
| SPFPharmacy.com | $2.61 | 60 | $9.95 | $156.45 |
| InhalersOnline.com | $2.66 | 56 | $0.00 | $149.20 |
Initial · 12.5 mg/500 mgfrom $53.12
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| CanadianPrescriptionDrugstore.com | $0.680 | 180 | $14.95 | $122.00Lowest |
| CanadaPharmacyPro.com | $0.750 | 180 | $14.95 | $134.54 |
| GoldStarMeds.com | $0.770 | 180 | $0.00 | $139.32 |
| LifeRxPharmacy.com | $0.790 | 180 | $14.95 | $142.57 |
| $0.800 | 180 | $14.95 | $143.29 | |
| $0.840 | 90 | $14.95 | $75.86 | |
| 1800RxOnline.com | $0.860 | 180 | $0.00 | $154.80 |
| LifeRxPharmacy.com | $0.890 | 60 | $14.95 | $53.12 |
| OffShoreCheapMeds.com | $0.950 | 180 | $14.95 | $171.80 |
| OffShoreCheapMeds.com | $1.01 | 90 | $14.95 | $90.95 |
| CanadianPharmacyAdvantage.com | $1.02 | 180 | Free | $184.15 |
| CanadaPharmacies.com | $1.08 | 180 | Free | $194.99 |
| InhalersOnline.com | $1.11 | 180 | $0.00 | $199.98 |
| CanadianPharmacyAdvantage.com | $1.26 | 60 | Free | $75.77 |
| CanadaPharmacies.com | $1.45 | 60 | Free | $86.99 |
| InhalersOnline.com | $1.47 | 60 | $0.00 | $87.99 |
| GoldStarMeds.com | $1.83 | 30 | $0.00 | $54.82 |
| 1800RxOnline.com | $2.03 | 30 | $0.00 | $60.91 |
| InhalersOnline.com | $2.08 | 180 | $0.00 | $373.74 |
| InhalersOnline.com | $2.33 | 60 | $0.00 | $139.73 |
| SPFPharmacy.com | $2.35 | 180 | $9.95 | $422.16 |
| SPFPharmacy.com | $2.61 | 60 | $9.95 | $156.45 |
Initial · 12.5 mg/850 mgfrom $149.43
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| CanadianPrescriptionDrugstore.com | $2.33 | 168 | $14.95 | $392.00Lowest |
| SPFPharmacy.com | $2.35 | 180 | $9.95 | $422.16 |
| $2.42 | 180 | $14.95 | $435.66 | |
| CanadaPharmacyPro.com | $2.49 | 180 | $14.95 | $448.92 |
| InhalersOnline.com | $2.50 | — | $0.00 | $419.40 |
| $2.50 | 120 | $14.95 | $299.93 | |
| SPFPharmacy.com | $2.61 | 60 | $9.95 | $156.45 |
| CanadaPharmacyPro.com | $2.63 | 120 | $14.95 | $315.91 |
| OffShoreCheapMeds.com | $2.65 | 180 | $14.95 | $477.23 |
| InhalersOnline.com | $2.67 | — | $0.00 | $149.43 |
| OffShoreCheapMeds.com | $2.73 | 120 | $14.95 | $327.92 |
| LifeRxPharmacy.com | $2.78 | 180 | $14.95 | $501.09 |
| LifeRxPharmacy.com | $2.87 | 120 | $14.95 | $344.32 |
| InhalersOnline.com | $2.88 | 180 | $0.00 | $518.70 |
| InhalersOnline.com | $3.24 | 60 | $0.00 | $194.30 |
Initial · 12.5 mg/1000 mgfrom $44.94
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| CanadianPrescriptionDrugstore.com | $0.670 | 180 | $14.95 | $120.00Lowest |
| LifeRxPharmacy.com | $0.670 | 180 | $14.95 | $121.32 |
| OffShoreCheapMeds.com | $0.690 | 180 | $14.95 | $124.15 |
| LifeRxPharmacy.com | $0.750 | 60 | $14.95 | $44.94 |
| GoldStarMeds.com | $0.770 | 180 | $0.00 | $139.32 |
| OffShoreCheapMeds.com | $0.770 | 60 | $14.95 | $45.98 |
| CanadaPharmacyPro.com | $0.780 | 180 | $14.95 | $139.91 |
| CanadianPharmacyAdvantage.com | $0.810 | 180 | Free | $146.32 |
| CanadaPharmacyPro.com | $0.820 | 120 | $14.95 | $98.46 |
| GoldStarMeds.com | $0.830 | 180 | $0.00 | $148.79 |
| 1800RxOnline.com | $0.860 | 180 | $0.00 | $154.80 |
| CanadaPharmacies.com | $0.870 | 180 | Free | $156.99 |
| CanadianPharmacyAdvantage.com | $0.930 | 60 | Free | $55.59 |
| CanadaPharmacies.com | $1.12 | 60 | Free | $66.99 |
| GoldStarMeds.com | $1.15 | 60 | $0.00 | $69.09 |
| InhalersOnline.com | $1.16 | 180 | $0.00 | $207.99 |
| InhalersOnline.com | $1.50 | 60 | $0.00 | $89.99 |
| GoldStarMeds.com | $1.50 | 168 | $0.00 | $252.70 |
| 1800RxOnline.com | $1.67 | 168 | $0.00 | $280.79 |
 BuyLowDrugs.com | $1.67 | 120 | $0.00 | $200.00 |
| InhalersOnline.com | $2.07 | 180 | $0.00 | $373.17 |
| 1800RxOnline.com | $2.10 | 56 | $0.00 | $117.71 |
| 1800RxOnline.com | $2.11 | 30 | $0.00 | $63.16 |
| SPFPharmacy.com | $2.35 | 180 | $9.95 | $422.16 |
| BuyLowDrugs.com | $2.40 | 60 | $0.00 | $144.00 |
| InhalersOnline.com | $2.50 | 56 | $0.00 | $139.99 |
| SPFPharmacy.com | $2.61 | 60 | $9.95 | $156.45 |
Generic · Defaultfrom $89.99
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| InhalersOnline.com | $0.800 | 200 | $0.00 | $160.00Lowest |
| InhalersOnline.com | $0.900 | 100 | $0.00 | $89.99 |
Brand · Defaultfrom $89.99
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| InhalersOnline.com | $0.800 | 200 | $0.00 | $160.00Lowest |
| InhalersOnline.com | $0.900 | 100 | $0.00 | $89.99 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Synjardy Xr.
Frequently asked questions
How much does Synjardy Xr (Synjardy) cost without insurance?
Our most recent US pharmacy data shows a low of roughly $243.66 for Synjardy Xr with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
What do Canadian pharmacies charge for Synjardy Xr (Synjardy)?
We found Canadian pricing for Synjardy Xr starting near $0.670 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.
Why is Synjardy Xr (Synjardy) priced differently in the US and Canada?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. Check the comparison table above for the specific numbers on Synjardy Xr.
Does Synjardy Xr have a generic equivalent?
Generic and brand-name pricing for Synjardy Xr is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
Is a generic version of Synjardy XR available?
No. Synjardy XR is a brand-name combination medication. There is currently no FDA-approved generic equivalent that a pharmacist can substitute.
What is Synjardy XR and how does it work?
Synjardy XR is an FDA-approved combination drug containing metformin and empagliflozin, prescribed alongside diet and exercise to manage high blood sugar in adults with Type 2 diabetes. By improving blood sugar control, it can help reduce the risk of serious diabetes-related complications like nerve damage, vision loss, kidney problems, and cardiovascular events. It works through three main actions: it helps restore the body's sensitivity to insulin, decreases the amount of sugar produced by the liver, and increases the removal of excess sugar through the kidneys.
How does Synjardy differ from Synjardy XR?
Both Synjardy and Synjardy XR contain the same active ingredients, metformin and empagliflozin, and are FDA-approved for Type 2 diabetes. The key difference lies in their release formulations and dosing schedules. Synjardy is an immediate-release tablet taken twice daily. Synjardy XR is an extended-release formulation designed to be taken just once daily, which may offer greater convenience for some patients.