Upneeq Cost Without Insurance — US Pharmacy Price Guide

Our most recent US pharmacy data shows a low of roughly $205.75 for Upneeq with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Generic and brand-name pricing for Upneeq is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.

The cost with insurance depends entirely on your specific plan's formulary, which dictates coverage and copay or coinsurance amounts. Some plans may cover Upneeq, while others may not. It's essential to contact your insurance provider directly for details on your coverage. If your plan does not cover the medication, or if your copay is high, you can compare the price using a pharmacy savings program or discount card against your insurance cost. Patients with Medicare or Medicaid should check their plan's coverage; if there is a gap, alternative savings options may be available to help manage the expense.

No. Upneeq is a brand-name drug produced by RVL Pharmaceuticals, and a generic equivalent (oxymetazoline hydrochloride ophthalmic solution) is not available at this time. Patients must use the brand-name product.