Vytorin (Ezetimibe-Simvastatin) Rx Price Comparison: US vs Canada — Save Up to 86% in the US

At the US pharmacies in our data, the lowest listed discount-card price for Ezetimibe-Simvastatin is around $37.44. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.

Yes — Cost Plus Drugs lists Ezetimibe-Simvastatin at roughly $0.065 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

Canadian pharmacy listings in our data show Ezetimibe-Simvastatin priced from about $0.470 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.

The generic Ezetimibe-Simvastatin is typically covered under Medicare Part D or Medicare Advantage prescription drug plans, though the brand-name version, Vytorin, usually is not. For beneficiaries without Medicare coverage or those facing high copays, presenting a pharmacy discount coupon at the time of purchase can provide an alternative pricing option, potentially reducing the cost significantly.

Ezetimibe-Simvastatin is the generic version of the brand-name drug Vytorin. It is manufactured by several companies, including Amneal, Dr. Reddy's, ANI, and Glenmark. If your prescription is for Vytorin, you can ask your doctor or pharmacist about switching to the generic to save money, as it contains the same active ingredients.

Ezetimibe-Simvastatin is a once-daily oral tablet that combines two cholesterol-lowering agents. Simvastatin belongs to the statin class, which works in the liver to inhibit the production of LDL cholesterol and may help stabilize existing plaque in blood vessels. Ezetimibe works in the small intestine to block the absorption of cholesterol from food. This dual-action approach is used to treat high cholesterol, including the inherited form Homozygous Familial Hypercholesterolemia (HoFH), to lower the risk of cardiovascular events. It is usually taken in the evening, with or without food.