US pharmacy pricing
Xatmep Prices at US Pharmacies
Lowest price found · US pharmacies
$2,520.74/fill
for Xatmep, across the pharmacies in our data
US pharmacy prices — 2.5mg/ml
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $2,520.74Lowest | $2,523.74 | $182.81 |
 Harris Teeter Pharmacy | $2,520.74Lowest | $2,523.74 | $182.81 |
 CVS Pharmacy | $2,630.95 | $2,633.95 | $182.81 |
 Food Lion | $2,634.91 | $2,634.91 | $182.81 |
 Walgreens | $2,646.11 | $2,649.11 | $182.81 |
 Publix | $2,662.81 | $2,665.81 | $182.81 |
 Walmart Neighborhood Market | $2,706.68 | $2,709.68 | $182.81 |
 Walmart Pharmacy | $2,706.68 | $2,709.68 | $182.81 |
 Costco | $2,721.62 | $2,724.62 | $182.81 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Xatmep.
Frequently asked questions
What's the cash price for Xatmep (Xatmep) in the US?
At the US pharmacies in our data, the lowest listed discount-card price for Xatmep is around $2,520.74. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Is a generic version of Xatmep available?
Generic and brand-name pricing for Xatmep is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
Is Xatmep covered by Medicare, and what would it cost?
Coverage for Xatmep under Medicare Part D prescription drug plans is not universal and varies by plan. If it is not covered under Part D, it may potentially be covered under Medicare Part B, depending on the clinical setting and administration. For Medicare beneficiaries without coverage, significant savings may be available through manufacturer coupons or pharmacy discount programs at many national and independent pharmacies.
Is a generic version of Xatmep available?
Xatmep is currently the only brand-name oral solution formulation of methotrexate. A generic methotrexate oral solution is not supplied at this time, though generic methotrexate is available in other dosage forms, such as tablets.
What is Xatmep and how does it work?
Xatmep is the brand name for a methotrexate oral solution. It is prescribed for two main conditions: acute lymphoblastic leukemia (ALL) and active polyarticular juvenile idiopathic arthritis (pJIA) that has not responded sufficiently to first-line treatments like non-steroidal anti-inflammatory drugs (NSAIDs). Methotrexate is classified as an antimetabolite. It works by blocking essential metabolic processes within cells, preventing them from dividing and growing. In cancer, this action helps stop tumor cells. In pJIA—a form of childhood arthritis affecting five or more joints—it suppresses the overactive immune cells that cause inflammation and joint damage. Xatmep is provided as a weekly oral solution for patients, including children, who cannot swallow tablets, typically when lower doses are required. The exact dosage is determined by a healthcare provider based on the specific condition being treated.