Full price comparison · US & Canada
How Much Does Xifaxan Cost?
Price comparison
See both prices
We don't have a directly comparable per-unit price for Xifaxan yet — the full breakdown is below.
US · discount card
$370.95
per fill
Lowest listed pharmacy price
Canada
$0.300
per tablet
Lowest listed pharmacy price
US pharmacy prices — 550mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $370.95Lowest | $373.95 | $37.99 |
 Harris Teeter Pharmacy | $370.95Lowest | $373.95 | $37.99 |
 Walmart Neighborhood Market | $404.30 | $407.30 | $37.99 |
 Walmart Pharmacy | $404.30 | $407.30 | $37.99 |
 Walgreens | $405.82 | $408.82 | $37.99 |
 Publix | $411.07 | $414.07 | $37.99 |
 CVS Pharmacy | $416.14 | $419.14 | $37.99 |
 Costco | $417.75 | $420.75 | $37.99 |
 Food Lion | $419.52 | $419.52 | $37.99 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
Initial · 200 mgfrom $68.84
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 CanadianPrescriptionDrugstore.com | $3.33 | 180 | $14.95 | $600.00Lowest |
 InhalersOnline.com | $3.92 | 90 | $0.00 | $353.00 |
| $4.35 | 90 | $14.95 | $391.50 | |
 OffShoreCheapMeds.com | $4.51 | 90 | $14.95 | $405.79 |
 LifeRxPharmacy.com | $4.60 | 90 | $14.95 | $414.37 |
| $5.34 | 27 | $14.95 | $144.12 | |
| OffShoreCheapMeds.com | $5.53 | 27 | $14.95 | $149.38 |
 GoldStarMeds.com | $5.63 | 90 | $0.00 | $506.33 |
| LifeRxPharmacy.com | $5.65 | 27 | $14.95 | $152.54 |
 1800RxOnline.com | $5.97 | 90 | $0.00 | $537.21 |
| GoldStarMeds.com | $6.33 | 27 | $0.00 | $170.95 |
| 1800RxOnline.com | $7.03 | 27 | $0.00 | $189.94 |
| InhalersOnline.com | $7.65 | 9 | $0.00 | $68.84 |
Generic · 200 mgfrom $22.25
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| LifeRxPharmacy.com | $0.300 | 180 | $14.95 | $53.74Lowest |
| $0.300 | 180 | $14.95 | $53.88 | |
| LifeRxPharmacy.com | $0.320 | 90 | $14.95 | $28.55 |
| $0.320 | 90 | $14.95 | $28.63 | |
| OffShoreCheapMeds.com | $0.340 | 180 | $14.95 | $61.58 |
 CanadaPharmacyPro.com | $0.350 | 90 | $14.95 | $31.52 |
| OffShoreCheapMeds.com | $0.360 | 90 | $14.95 | $32.71 |
| CanadaPharmacyPro.com | $0.370 | 60 | $14.95 | $22.25 |
| CanadianPrescriptionDrugstore.com | $0.380 | 200 | $14.95 | $75.00 |
 CanadianPharmacyAdvantage.com | $0.440 | 200 | Free | $87.43 |
| InhalersOnline.com | $0.490 | 300 | $0.00 | $147.66 |
 CanadaPharmacies.com | $0.490 | 200 | Free | $97.99 |
| CanadianPharmacyAdvantage.com | $0.490 | 100 | Free | $49.23 |
| CanadianPrescriptionDrugstore.com | $0.550 | 100 | $14.95 | $55.00 |
| InhalersOnline.com | $0.570 | 100 | $0.00 | $56.97 |
| CanadaPharmacies.com | $0.600 | 100 | Free | $59.99 |
| GoldStarMeds.com | $0.990 | 60 | $0.00 | $59.33 |
| 1800RxOnline.com | $1.10 | 60 | $0.00 | $65.92 |
| GoldStarMeds.com | $1.15 | 30 | $0.00 | $34.61 |
| 1800RxOnline.com | $1.28 | 30 | $0.00 | $38.46 |
Generic · 400 mgfrom $42.61
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| LifeRxPharmacy.com | $0.580 | 180 | $14.95 | $104.86Lowest |
| CanadianPrescriptionDrugstore.com | $0.590 | 200 | $14.95 | $118.00 |
| LifeRxPharmacy.com | $0.620 | 90 | $14.95 | $55.71 |
| CanadaPharmacyPro.com | $0.650 | 180 | $14.95 | $117.63 |
| $0.670 | 90 | $14.95 | $60.36 | |
| OffShoreCheapMeds.com | $0.680 | 90 | $14.95 | $61.47 |
| CanadianPrescriptionDrugstore.com | $0.690 | 100 | $14.95 | $68.50 |
| $0.710 | 60 | $14.95 | $42.61 | |
| OffShoreCheapMeds.com | $0.720 | 60 | $14.95 | $43.39 |
| CanadianPharmacyAdvantage.com | $0.780 | 200 | Free | $155.54 |
| InhalersOnline.com | $0.800 | 200 | $0.00 | $160.00 |
| CanadaPharmacies.com | $0.830 | 200 | Free | $166.99 |
| CanadianPharmacyAdvantage.com | $0.830 | 100 | Free | $82.89 |
| CanadaPharmacyPro.com | $0.840 | 60 | $14.95 | $50.36 |
| InhalersOnline.com | $0.900 | 100 | $0.00 | $89.70 |
| CanadaPharmacies.com | $0.940 | 100 | Free | $93.99 |
 BuyLowDrugs.com | $1.11 | 100 | $0.00 | $111.00 |
| GoldStarMeds.com | $1.19 | 60 | $0.00 | $71.28 |
| 1800RxOnline.com | $1.32 | 60 | $0.00 | $79.20 |
| GoldStarMeds.com | $1.61 | 30 | $0.00 | $48.26 |
| 1800RxOnline.com | $1.79 | 30 | $0.00 | $53.62 |
Brand · 200 mgfrom $22.25
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| LifeRxPharmacy.com | $0.300 | 180 | $14.95 | $53.74Lowest |
| $0.300 | 180 | $14.95 | $53.88 | |
| LifeRxPharmacy.com | $0.320 | 90 | $14.95 | $28.55 |
| $0.320 | 90 | $14.95 | $28.63 | |
| OffShoreCheapMeds.com | $0.340 | 180 | $14.95 | $61.58 |
| CanadaPharmacyPro.com | $0.350 | 90 | $14.95 | $31.52 |
| OffShoreCheapMeds.com | $0.360 | 90 | $14.95 | $32.71 |
| CanadaPharmacyPro.com | $0.370 | 60 | $14.95 | $22.25 |
| CanadianPrescriptionDrugstore.com | $0.380 | 200 | $14.95 | $75.00 |
| CanadianPharmacyAdvantage.com | $0.440 | 200 | Free | $87.43 |
| InhalersOnline.com | $0.490 | 300 | $0.00 | $147.66 |
| CanadaPharmacies.com | $0.490 | 200 | Free | $97.99 |
| CanadianPharmacyAdvantage.com | $0.490 | 100 | Free | $49.23 |
| CanadianPrescriptionDrugstore.com | $0.550 | 100 | $14.95 | $55.00 |
| InhalersOnline.com | $0.570 | 100 | $0.00 | $56.97 |
| CanadaPharmacies.com | $0.600 | 100 | Free | $59.99 |
| GoldStarMeds.com | $0.990 | 60 | $0.00 | $59.33 |
| 1800RxOnline.com | $1.10 | 60 | $0.00 | $65.92 |
| GoldStarMeds.com | $1.15 | 30 | $0.00 | $34.61 |
| 1800RxOnline.com | $1.28 | 30 | $0.00 | $38.46 |
Brand · 400 mgfrom $42.61
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
| LifeRxPharmacy.com | $0.580 | 180 | $14.95 | $104.86Lowest |
| CanadianPrescriptionDrugstore.com | $0.590 | 200 | $14.95 | $118.00 |
| LifeRxPharmacy.com | $0.620 | 90 | $14.95 | $55.71 |
| CanadaPharmacyPro.com | $0.650 | 180 | $14.95 | $117.63 |
| $0.670 | 90 | $14.95 | $60.36 | |
| OffShoreCheapMeds.com | $0.680 | 90 | $14.95 | $61.47 |
| CanadianPrescriptionDrugstore.com | $0.690 | 100 | $14.95 | $68.50 |
| $0.710 | 60 | $14.95 | $42.61 | |
| OffShoreCheapMeds.com | $0.720 | 60 | $14.95 | $43.39 |
| CanadianPharmacyAdvantage.com | $0.780 | 200 | Free | $155.54 |
| InhalersOnline.com | $0.800 | 200 | $0.00 | $160.00 |
| CanadaPharmacies.com | $0.830 | 200 | Free | $166.99 |
| CanadianPharmacyAdvantage.com | $0.830 | 100 | Free | $82.89 |
| CanadaPharmacyPro.com | $0.840 | 60 | $14.95 | $50.36 |
| InhalersOnline.com | $0.900 | 100 | $0.00 | $89.70 |
| CanadaPharmacies.com | $0.940 | 100 | Free | $93.99 |
| BuyLowDrugs.com | $1.11 | 100 | $0.00 | $111.00 |
| GoldStarMeds.com | $1.19 | 60 | $0.00 | $71.28 |
| 1800RxOnline.com | $1.32 | 60 | $0.00 | $79.20 |
| GoldStarMeds.com | $1.61 | 30 | $0.00 | $48.26 |
| 1800RxOnline.com | $1.79 | 30 | $0.00 | $53.62 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Xifaxan.
Frequently asked questions
What's the cash price for Xifaxan (Xifaxan) in the US?
At the US pharmacies in our data, the lowest listed discount-card price for Xifaxan is around $370.95. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
How much does Xifaxan (Xifaxan) cost in Canada?
Canadian pharmacy listings in our data show Xifaxan priced from about $0.300 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.
Why does Xifaxan (Xifaxan) cost more in one country than the other?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. Check the comparison table above for the specific numbers on Xifaxan.
Is a generic version of Xifaxan available?
Generic and brand-name pricing for Xifaxan is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
How much can I expect to pay for Xifaxan with insurance?
The cost of Xifaxan with insurance varies significantly based on your specific plan's formulary and pharmacy network. While Xifaxan is commonly covered by insurance plans, you will likely be responsible for a copay or coinsurance. To determine your exact cost, contact your insurance provider or speak with your pharmacist.
Is Xifaxan covered by Medicare, and what is the typical cost?
Xifaxan is often included on the formularies of Medicare Part D and Medicare Advantage plans. Your out-of-pocket cost under Medicare will depend on your plan's coverage details and which benefit phase you are in, such as the deductible or coverage gap. For those facing high costs even with coverage, checking with your pharmacy about potential savings options, including manufacturer programs, may be helpful.
What options are available to help save money on Xifaxan?
Several resources may help lower the cost of Xifaxan. The manufacturer, Salix Pharmaceuticals, offers a savings card for eligible patients with commercial insurance. For uninsured or underinsured patients who qualify, patient assistance programs like those from the Patient Access Network Foundation (PAN) or the Bausch Health Patient Assistance Program may provide the medication at a reduced cost or for free. Contact the manufacturer directly for details on coupons, rebates, and other savings. Additionally, many pharmacies accept general prescription discount cards that are widely available to all patients.