Zafirlukast (Zafirlukast) Rx Price Comparison: US vs Canada — Save Up to 96% in Canada

Our most recent US pharmacy data shows a low of roughly $34.73 for Zafirlukast with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.

Yes — Cost Plus Drugs lists Zafirlukast at roughly $12.31 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.

We found Canadian pricing for Zafirlukast starting near $0.500 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.

Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the Canadian price coming in lower — but that isn't true for every drug, so it's worth checking each medication individually rather than assuming.

Zafirlukast is the generic version of the asthma prevention drug Accolate.

Zafirlukast is a generic prescription drug used for the long-term prevention of asthma symptoms in adults and children aged 5 years and older. It is not a rescue medication and should not be used to stop an active asthma attack; a fast-acting inhaler is needed for that purpose. Zafirlukast is usually taken as part of a broader asthma management plan that may include other medications like inhaled corticosteroids. It functions by blocking leukotrienes, chemicals that cause inflammation and constriction in the airways. The tablets should be taken on an empty stomach, either one hour before or two hours after a meal. Zafirlukast is not suitable for everyone. It is contraindicated for people with known hypersensitivity to the drug or active liver disease. It is also not recommended for use while breastfeeding. Pregnant individuals or those planning pregnancy should discuss its use with their doctor. Before starting treatment, inform your healthcare provider about all your medical conditions and any other medications, supplements, or vitamins you are taking.

Common side effects of zafirlukast can include headache, nausea, gastrointestinal upset, diarrhea, general infections, and insomnia. The medication can also affect liver function. Although rare, serious mood and behavioral changes have been reported, including depression, agitation, aggression, and suicidal thoughts. It is critical to contact your doctor immediately if you or a caregiver observe any such changes. Severe allergic reactions, while very uncommon, may present with hives, rash, swelling, or difficulty breathing and require emergency medical attention. Another rare but serious condition involves inflammation of blood vessels, with symptoms that can mimic the flu or include sinus pain, skin rash, or numbness in the limbs. This is not an exhaustive list of possible side effects. Discuss any concerns with your prescribing physician.