US pharmacy pricing
Sapropterin Dihydrochloride Cost Without Insurance — US Pharmacy Price Guide
Lowest price found · US pharmacies
$2,180.79/fill
for Sapropterin Dihydrochloride, across the pharmacies in our data
Discount card
$2,180.79
per fill
Lowest listed pharmacy price
Cost Plus Drugs
$8.35
per unit
Published price, no card needed
US pharmacy prices — 500mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Walgreens | $2,180.79Lowest | $2,183.79 | $2,352.45 |
 Publix | $3,345.09 | $3,348.09 | $2,352.45 |
 Kroger Pharmacy | $4,897.08 | $4,900.08 | $2,352.45 |
 Harris Teeter Pharmacy | $4,897.08 | $4,900.08 | $2,352.45 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Sapropterin Dihydrochloride.
Frequently asked questions
Is Sapropterin Dihydrochloride expensive if I don't have insurance?
At the US pharmacies in our data, the lowest listed discount-card price for Sapropterin Dihydrochloride is around $2,180.79. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Can I buy Sapropterin Dihydrochloride at a Cost Plus Drugs price?
Yes — Cost Plus Drugs lists Sapropterin Dihydrochloride at roughly $8.35 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
Is a generic version of Sapropterin Dihydrochloride available?
Generic and brand-name pricing for Sapropterin Dihydrochloride is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
How can I find out what I'll pay for Sapropterin Dihydrochloride with my insurance?
The cost of Sapropterin Dihydrochloride with insurance depends entirely on the details of your specific health plan. Coverage, copays, and deductibles vary widely, so it's essential to contact your insurance provider directly to confirm if this medication is on your plan's formulary and what your out-of-pocket expense would be. If your plan does not cover the drug or if your copay is high, you may explore other options. Independent pharmacy savings programs can sometimes offer a lower price than your insurance copay, and this can be a useful alternative for patients with Medicare, Medicaid, or commercial insurance. It's advisable to compare the price offered by such a program with your insurance copay at the pharmacy to ensure you get the best available rate.