US pharmacy pricing
Where to Find the Cheapest Zosyn Price
Lowest price found · US pharmacies
$32.06/fill
for Piperacillin Sod-Tazobactam So, across the pharmacies in our data
US pharmacy prices — 4-0.5gm/100ml
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 CVS Pharmacy | $32.06Lowest | $35.06 | $3.49 |
 Publix | $50.31 | $53.31 | $3.49 |
 Walgreens | $57.41 | $60.41 | $3.49 |
 Kroger Pharmacy | $60.30 | $63.30 | $3.49 |
 Harris Teeter Pharmacy | $60.30 | $63.30 | $3.49 |
 Walmart Neighborhood Market | $67.36 | $70.36 | $3.49 |
 Walmart Pharmacy | $67.36 | $70.36 | $3.49 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Piperacillin Sod-Tazobactam So.
Frequently asked questions
How much does Piperacillin Sod-Tazobactam So (Zosyn) cost without insurance?
At the US pharmacies in our data, the lowest listed discount-card price for Piperacillin Sod-Tazobactam So is around $32.06. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Is a generic version of Piperacillin Sod-Tazobactam So available?
Generic and brand-name pricing for Piperacillin Sod-Tazobactam So is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
Is Zosyn covered by Medicare, and what are the costs if it is not?
Zosyn is often excluded from standard Medicare Part D coverage. Without coverage, patients are responsible for the full retail price. To manage this expense, you can explore prescription discount cards or coupons accepted at local and national pharmacy chains. Checking with pharmacies directly or using a mobile app for a savings program can help identify participating locations near you.
Is a generic version of Zosyn available?
Yes. The generic name for Zosyn is piperacillin-tazobactam. It is FDA-approved and manufactured by companies including Baxter International Inc. and Pfizer Inc.
What is Zosyn and what conditions does it treat?
Zosyn is a brand-name, intravenous antibiotic combination used to treat serious bacterial infections. It contains piperacillin, a penicillin-type antibiotic, and tazobactam, which protects piperacillin from being broken down by certain bacterial enzymes. It is effective for infections such as pneumonia, complicated skin infections, intra-abdominal infections, and severe pelvic infections. Because it is an injectable medication, it is administered by a healthcare professional in a clinical setting. It is critical to inform your doctor of your full medical history, especially regarding kidney problems, electrolyte imbalances, bleeding disorders, cystic fibrosis, or allergies to penicillin or cephalosporin antibiotics. Even if symptoms improve, the full course of treatment must be completed to prevent antibiotic resistance. Zosyn is not effective against viral illnesses like the common cold or flu.