US pharmacy pricing
Zynrelef Prices at US Pharmacies
Lowest price found · US pharmacies
$297.63/fill
for Zynrelef, across the pharmacies in our data
US pharmacy prices — 14ml of 400-12mg/14ml
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Kroger Pharmacy | $297.63Lowest | $300.63 | $265.42 |
 Harris Teeter Pharmacy | $297.63Lowest | $300.63 | $265.42 |
 Walgreens | $313.89 | $316.89 | $265.42 |
 Publix | $316.96 | $319.96 | $265.42 |
 Walmart Neighborhood Market | $319.91 | $322.91 | $265.42 |
 Walmart Pharmacy | $319.91 | $322.91 | $265.42 |
 Costco | $321.21 | $324.21 | $265.42 |
 CVS Pharmacy | $327.60 | $330.60 | $265.42 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Zynrelef.
Frequently asked questions
How much does Zynrelef (Zynrelef) cost without insurance?
At the US pharmacies in our data, the lowest listed discount-card price for Zynrelef is around $297.63. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Is a generic version of Zynrelef available?
Generic and brand-name pricing for Zynrelef is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
How much does Zynrelef cost with insurance coverage?
The cost of Zynrelef with insurance depends entirely on the details of your specific plan, including whether it is covered on your formulary and what your copay or coinsurance would be. It is best to contact your insurance provider directly for coverage and cost information. If your plan does not cover Zynrelef, or if your copay is high, you may explore alternative savings options such as pharmacy discount programs. These programs can sometimes be used in conjunction with government insurance like Medicare or Medicaid when they do not fully cover the medication's cost, but it's important to compare the final price from all available sources.
Is a generic form of Zynrelef available?
Zynrelef is a brand-name medication developed by Heron Therapeutics. Currently, there is no FDA-approved generic equivalent available on the market.