Full price comparison · US & Canada
How Much Does Letairis Cost?
Price comparison
See both prices
We don't have a directly comparable per-unit price for Ambrisentan yet — the full breakdown is below.
US · discount card
$273.08
per fill
Lowest listed pharmacy price
Canada
$8.40
per tablet
Lowest listed pharmacy price
US pharmacy prices — 10mg
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 Walgreens | $273.08Lowest | $276.08 | $469.91 |
 Food Lion | $435.50 | $435.50 | $469.91 |
 Costco | $1,381.92 | $1,381.92 | $469.91 |
 Publix | $5,018.16 | $5,021.16 | $469.91 |
 Kroger Pharmacy | $7,488.80 | $7,491.80 | $469.91 |
 Harris Teeter Pharmacy | $7,488.80 | $7,491.80 | $469.91 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
Initial · 10 mg
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 InhalersOnline.com | $8.40 | 90 | $0.00 | $756.09Lowest |
| InhalersOnline.com | $11.07 | 10 | $0.00 | $110.68 |
 SPFPharmacy.com | $145.41 | 90 | $9.95 | $13,086.57 |
| InhalersOnline.com | $146.61 | 90 | $0.00 | $13,195.29 |
| SPFPharmacy.com | $146.70 | 30 | $9.95 | $4,401.08 |
| InhalersOnline.com | $148.33 | 30 | $0.00 | $4,450.02 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Ambrisentan.
Frequently asked questions
How much does Ambrisentan (Letairis) cost without insurance?
Our most recent US pharmacy data shows a low of roughly $273.08 for Ambrisentan with a standard discount card. That figure moves with dosage and quantity — check the comparison table for the exact combination you need.
What do Canadian pharmacies charge for Ambrisentan (Letairis)?
We found Canadian pricing for Ambrisentan starting near $8.40 per tablet in USD terms. That's before any shipping charge, which the table above breaks out separately.
Why is Ambrisentan (Letairis) priced differently in the US and Canada?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. Check the comparison table above for the specific numbers on Ambrisentan.
Does Ambrisentan have a generic equivalent?
Generic and brand-name pricing for Ambrisentan is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
How much will I pay for Ambrisentan with my insurance plan?
The cost of Ambrisentan with insurance varies significantly based on the specific details of your plan, such as your deductible, copay, or coinsurance. You should contact your insurance provider directly to confirm coverage and your exact out-of-pocket expense. If your plan does not cover Ambrisentan, or if your copay is high, you may find that a pharmacy discount program offers a competitive price. This can also be an option for patients with Medicare or Medicaid if the prescription is not covered.
What is the brand-name version of Ambrisentan?
Ambrisentan is the generic form of the brand-name drug Letairis. Both contain the same active ingredient and are used for the same medical conditions. The generic version, Ambrisentan, is typically available at a significantly lower cost than Letairis. For example, a 30-day supply of 10 mg tablets may be obtained for a fraction of the brand-name price through various pharmacy savings programs.