Full price comparison · US & Canada
Apriso (Mesalamine Er) Rx Price Comparison: US vs Canada — Save Up to 75% in the US
Cheaper in the US
0%
lower price for Mesalamine Er, based on the lowest comparable per-unit prices we found
US · discount card
$40.10
per fill
Lowest listed pharmacy price
US · Cost Plus Drugs
$0.656
per unit
Published price, no card needed
Canada
$0.580
per tablet
Lowest listed pharmacy price
US pharmacy prices — 0.375gm
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 CVS Pharmacy | $40.10Lowest | $43.10 | $20.27 |
 Publix | $75.98 | $75.98 | $20.27 |
 Walgreens | $79.35 | $82.35 | $20.27 |
 Costco | $84.99 | $84.99 | $20.27 |
 Food Lion | $89.60 | $89.60 | $20.27 |
 Kroger Pharmacy | $132.68 | $135.68 | $20.27 |
 Harris Teeter Pharmacy | $132.68 | $135.68 | $20.27 |
 Walmart Neighborhood Market | $134.57 | $137.57 | $20.27 |
 Walmart Pharmacy | $134.57 | $137.57 | $20.27 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Canadian pharmacy prices
Initial · 800 mg
| Pharmacy | Price / tablet | Pack size | Shipping | Total |
|---|---|---|---|---|
 GoldStarMeds.com | $0.580 | 90 | $0.00 | $52.59Lowest |
 LifeRxPharmacy.com | $0.600 | 360 | $14.95 | $215.29 |
 1800RxOnline.com | $0.650 | 90 | $0.00 | $58.43 |
 CanadianPrescriptionDrugstore.com | $1.07 | 270 | $14.95 | $290.00 |
 CanadianPharmacyAdvantage.com | $1.08 | 270 | Free | $290.46 |
 CanadaPharmacies.com | $1.12 | 270 | Free | $301.99 |
 CanadaPharmacyPro.com | $1.12 | 360 | $14.95 | $404.59 |
| $1.13 | 360 | $14.95 | $406.63 | |
 BuyLowDrugs.com | $1.17 | 540 | $0.00 | $631.00 |
 InhalersOnline.com | $1.21 | 504 | $0.00 | $610.20 |
 OffShoreCheapMeds.com | $1.21 | 180 | $14.95 | $218.57 |
| $1.23 | 180 | $14.95 | $221.86 | |
| CanadianPharmacyAdvantage.com | $1.24 | 90 | Free | $111.20 |
| CanadaPharmacyPro.com | $1.25 | 180 | $14.95 | $225.29 |
| InhalersOnline.com | $1.25 | 540 | $0.00 | $674.34 |
| BuyLowDrugs.com | $1.27 | 270 | $0.00 | $343.00 |
| BuyLowDrugs.com | $1.34 | 180 | $0.00 | $241.00 |
| CanadaPharmacies.com | $1.36 | 90 | Free | $121.99 |
| OffShoreCheapMeds.com | $1.48 | 270 | $14.95 | $400.61 |
| InhalersOnline.com | $1.55 | 90 | $0.00 | $139.13 |
| InhalersOnline.com | $2.11 | 84 | $0.00 | $177.44 |
| LifeRxPharmacy.com | $2.19 | 180 | $14.95 | $394.59 |
Canadian prices are converted to USD at the time of listing and shown before any duties. Shipping and delivery times vary by pharmacy.
Frequently asked questions
Is Mesalamine Er (Apriso) expensive if I don't have insurance?
At the US pharmacies in our data, the lowest listed discount-card price for Mesalamine Er is around $40.10. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Can I buy Mesalamine Er (Apriso) at a Cost Plus Drugs price?
Yes — Cost Plus Drugs lists Mesalamine Er at roughly $0.656 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
How much does Mesalamine Er (Apriso) cost in Canada?
Canadian pharmacy listings in our data show Mesalamine Er priced from about $0.580 per tablet (converted to USD), before shipping. Pack size and pharmacy both affect the final total — see the Canada pricing table for specifics.
Why does Mesalamine Er (Apriso) cost more in one country than the other?
Drug pricing is set separately in each country through different negotiation, regulatory, and distribution systems, so the same medication can legitimately carry different price tags on either side of the border. In this case, our data shows the US price is actually the lower of the two once a program like Cost Plus Drugs is factored in — the assumption that Canada is always cheaper doesn't hold for every drug.
How much will I pay for Apriso with my insurance?
Your out-of-pocket cost for Apriso with insurance depends on your specific plan's formulary, deductible, and copay structure, so it can vary widely. It's advisable to check with your pharmacist or insurer for the exact amount. In some cases, the cash price for the generic version, potentially with a pharmacy savings program, could be lower than your insurance copay. You can ask your pharmacist to compare the pricing options available to you.
Are there generic alternatives to Apriso?
Yes. Apriso is the brand-name version of the drug mesalamine. Several pharmaceutical companies manufacture generic mesalamine extended-release capsules.
What is Apriso used for?
Apriso is prescribed to adults for the maintenance of remission in ulcerative colitis, a type of inflammatory bowel disease. It helps prevent the return of symptoms like rectal bleeding, abdominal pain, and diarrhea. As an aminosalicylate, its primary action is to reduce inflammation and swelling in the colon.