US pharmacy pricing
Denavir Cost Without Insurance — US Pharmacy Price Guide
Lowest price found · US pharmacies
$124.63/fill
for Penciclovir, across the pharmacies in our data
Discount card
$124.63
per fill
Lowest listed pharmacy price
Cost Plus Drugs
$116.91
per unit
Published price, no card needed
US pharmacy prices — 5gm of 1%
| Pharmacy | Discount-card price | Regular cash price | Average retail |
|---|---|---|---|
 CVS Pharmacy | $124.63Lowest | $127.63 | $155.99 |
 Walgreens | $276.67 | $279.67 | $155.99 |
 Publix | $451.20 | $454.20 | $155.99 |
 Walmart Neighborhood Market | $536.74 | $539.74 | $155.99 |
 Walmart Pharmacy | $536.74 | $539.74 | $155.99 |
 Kroger Pharmacy | $657.88 | $660.88 | $155.99 |
 Harris Teeter Pharmacy | $657.88 | $660.88 | $155.99 |
 Food Lion | $708.78 | $708.78 | $155.99 |
 Costco | $710.78 | $710.78 | $155.99 |
"Discount-card price" reflects a standard prescription discount card, not insurance. Prices change often — confirm at the pharmacy before filling.
Interchangeable forms
Per RxNorm (U.S. National Library of Medicine), these share the same active ingredient and strength as Penciclovir.
Frequently asked questions
What's the cash price for Penciclovir (Denavir) in the US?
At the US pharmacies in our data, the lowest listed discount-card price for Penciclovir is around $124.63. Prices vary by pharmacy, dosage, and pack size, so use the table above to compare specific options near you.
Can I buy Penciclovir (Denavir) at a Cost Plus Drugs price?
Yes — Cost Plus Drugs lists Penciclovir at roughly $116.91 per unit, a published price with no membership card or coupon involved. See the three-price comparison above for how that stacks up against discount-card pharmacies.
Is a generic version of Penciclovir available?
Generic and brand-name pricing for Penciclovir is broken out in the tables above where both exist in our data. Generic versions are typically the lower-cost option, but availability depends on the specific formulation and dosage.
Is a generic version of Denavir available?
No. Denavir is a brand-name medication manufactured by Mylan Pharmaceuticals, Inc. A generic equivalent containing penciclovir is not currently on the market.
What is Denavir and how is it used?
Denavir is a prescription topical cream used to treat symptoms of herpes simplex virus infections, specifically cold sores (herpes labialis). Its active ingredient is penciclovir, which is part of the antiviral drug class. It works by inhibiting the replication of the virus. For best results, apply the cream at the first sign of a cold sore, such as tingling, itching, or redness. The standard regimen for adults and children 12 years and older is to apply it every 2 hours while awake for a total of four days. Denavir is intended to heal sores and reduce associated pain, burning, and itching. It is for use only on the lips and face and is not a cure for herpes, nor does it prevent future outbreaks or stop the virus from spreading to others.
What side effects are associated with Denavir?
The most frequently reported side effects of Denavir are local reactions at the application site, including redness, burning, stinging, or numbness. If these effects become severe or bothersome, contact your healthcare provider for advice on managing discomfort. Do not use Denavir if you have a known allergy to penciclovir. This list is not exhaustive, so it is important to discuss all potential side effects and symptoms of an allergic reaction with your doctor or pharmacist before starting treatment.